Continuation of Type 1 Diabetes in Acute Pancreatitis: UF Health and AdventHealth
Official title: Continuation of Type 1 Diabetes in Acute Pancreatitis Consortium – UF Health and AdventHealth Combined Clinical Center
Funded at University of Florida · NIH-11417469 · Data updated 2026-11-12
A patient-facing overview of a long-term study tracking people with acute pancreatitis to understand how some develop type 1 diabetes later and what factors influence that process.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Florida NIH-funded |
| Lab location | 1 site (Gainesville, United States) |
| Project start | September 16, 2020 |
| Project end | July 31, 2030 |
| Funding year | 2026 |
| Award (this year) | $480,000 |
| NIH project number | 5U01DK127392-07 |
| Project ID | NIH-11417469 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults recently hospitalized for acute or acute relapsing pancreatitis who consent to long-term follow-up and genetic/biologic testing.
✕Less likely to help
Individuals without a history of pancreatitis or those unwilling to participate in long-term follow-up or genetic/biologic testing may not benefit.
What this research studies
This project continues a longitudinal group of people who have had acute pancreatitis to watch how many go on to develop type 1 diabetes and why. Researchers will collect genetic, immune, metabolic, tissue, and functional data to uncover pathways that link pancreatitis to diabetes. The study leverages UF Health and AdventHealth to recruit large numbers of patients and perform coordinated testing over time. Participants may contribute blood samples and health information to help identify risk factors and possible targets for prevention or treatment. The aim is to build a robust resource for understanding diabetes following acute pancreatitis and to guide future care.
Why it matters
Potential benefit: If successful, it could lead to earlier risk prediction and better prevention or management of diabetes after pancreatitis.
How similar studies have gone: The consortium builds on an established framework; ongoing studies in related cohorts have shown that pancreatitis can be linked to diabetes, with more work expected to clarify mechanisms.
Where this research is happening
-
University of Florida
Gainesville, United States Active
Researchers
- Principal investigator: Forsmark, Christopher E — University of Florida
- Study coordinator: Forsmark, Christopher E
Related research
Other NIH-funded projects on the same topics.
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Data Coordinating Center for Type 1 Diabetes in Acute Pancreatitis Consortium
A national effort to learn how pancreatitis-related Type 1 diabetes develops, by tracking patients and coordinating data to improve future care.
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Type 1 Diabetes in Acute Pancreatitis in Diabetes Patients at Stanford
A Stanford-led project helps people with brittle type 1 diabetes who also experience pancreatitis by following them in a long-term study to understand how acute pancreatitis affects diabetes.
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Type 1 Diabetes after Acute Pancreatitis: Immune Clues from the Pacific Northwest
A multi-center study follows adults after an acute pancreatitis episode to understand how some develop Type 1 diabetes and what immune factors are involved.
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Diabetes After Acute Pancreatitis: Understanding Progression and Genetics at Cedars-Sinai
This grant supports Cedars-Sinai’s clinical center as part of a national effort to study why some adults develop brittle type 1 diabetes after an acute pancreatitis episode and how genes influence this risk.
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Understanding how acute pancreatitis may lead to type 1 diabetes
This study is looking at how having acute pancreatitis might lead to type 1 diabetes, and it aims to find early warning signs and risk factors to help identify people who could be at risk for developing diabetes after pancreatitis.
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Cedars‑Sinai program on diabetes that follows acute pancreatitis
This program follows people who had acute pancreatitis to find biological and genetic signs that predict who will develop diabetes afterward.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.