Pancreas problems in diabetes, pancreatitis, and cancer
Official title: The Exocrine and Endocrine Pancreas in Type 2 Diabetes, Pancreatitis and Cancer
Funded at Mayo Clinic Rochester · NIH-11400293 · Data updated 2026-11-12
A nationwide group led by Mayo Clinic is joining forces to study how the pancreas is involved in type 2 diabetes, pancreatitis, and pancreatic cancer so providers can diagnose and treat these conditions better.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Mayo Clinic Rochester NIH-funded |
| Lab location | 1 site (Rochester, United States) |
| Project start | September 28, 2015 |
| Project end | June 30, 2030 |
| Funding year | 2026 |
| Award (this year) | $512,400 |
| NIH project number | 5U01DK108288-12 |
| Project ID | NIH-11400293 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults with type 2 diabetes, chronic pancreatitis, or pancreatic cancer who are or could be part of the CP CRC consortium and its ancillary studies.
✕Less likely to help
Patients not overlap with the diabetes, pancreatitis, or pancreatic cancer pathways or who are not engaged in the consortium may not directly benefit.
What this research studies
This project brings together multiple centers to study how the exocrine and endocrine pancreas relate to type 2 diabetes, chronic pancreatitis, and pancreatic cancer. It follows participants over time, collects tissue and biomarker data, and runs ancillary studies to understand disease pathways. The effort includes clinical recruitment, follow-up of thousands of existing participants, and plans for clinical trials in diabetes and smoking-related pancreatitis. Patients may contribute samples or participate in future studies as part of the consortium.
Why it matters
Potential benefit: If successful, the work could lead to earlier diagnosis, better treatment options, and new clinical trials for pancreas-related diseases.
How similar studies have gone: Past participation in CP CRC-related studies has enabled extensive biobank and biomarker work with ongoing recruitment and follow-up.
Where this research is happening
-
Mayo Clinic Rochester
Rochester, United States Active
Researchers
- Principal investigator: Vege, Santhi Swaroop — Mayo Clinic Rochester
- Study coordinator: Vege, Santhi Swaroop
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.