Safety and pain relief with stem cells for chronic pancreatitis

Who could benefit from this research

What this research studies

This project tests a stem cell treatment in people with chronic pancreatitis who suffer persistent pain. Researchers will study how mesenchymal stem cells affect pain pathways and inflammation, using careful monitoring for safety and dosing. If the therapy helps, patients could experience less pain and reduced reliance on opioids, with closer follow-up from their medical team. Participation would involve medical visits, possible cell infusions, and follow-up assessments over time.

Why it matters

Where this research is happening

• Medical University of South Carolina
  Charleston, United States Active

Researchers

• Principal investigator: Wang, Hongjun — Medical University of South Carolina
• Study coordinator: Wang, Hongjun

Related research

Other NIH-funded projects on the same topics.

• Chronic Pancreatitis and Related Conditions Data Center Supports Multi-Center Research

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  NIH research University of Tx Md Anderson Can Ctr · Houston, United States · NIH-11592146

• Malabsorption Blood Test for Exocrine Pancreatic Function in Chronic Pancreatitis

  A blood test (MBT) will help identify people with mild to moderate pancreatic fat malabsorption and show how well enzyme therapy improves their quality of life.

  NIH research University of Pittsburgh at Pittsburgh · Pittsburgh, United States · NIH-11415052

• Chronic Pancreatitis Clinical Research Cohort and Biorepository

  A long-term study at UF/Advent Health following adults with acute, relapsing, and chronic pancreatitis to build a detailed group with biospecimens and data for better diagnosis and personalized care.

  NIH research University of Florida · Gainesville, United States · NIH-11408761

• Cedars-Sinai Center leads research on chronic pancreatitis and pancreatic cancer

  A Cedars-Sinai research center is renewing its program to study chronic pancreatitis, diabetes-related pancreatic disease, and pancreatic cancer so doctors can better understand and treat these conditions.

  NIH research Cedars-Sinai Medical Center · Los Angeles, United States · NIH-11401819

• UPMC Center for Pancreatitis and Diabetes research program

  A specialized center at the University of Pittsburgh is advancing clinical and biological studies of chronic pancreatitis, recurrent acute pancreatitis, and diabetes to improve understanding and care.

  NIH research University of Pittsburgh at Pittsburgh · Pittsburgh, United States · NIH-11401437

• Chronic Pancreatitis Research Network to Understand Symptoms and Find Treatments

  This project advances studies of chronic pancreatitis to understand why some people progress and to test new ideas that could diagnose or slow the disease.

  NIH research Indiana University Indianapolis · Indianapolis, United States · NIH-11400539

About this research

1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.