Soy-and-tomato diet to lower inflammation in chronic pancreatitis
Official title: A dietary intervention clinical trial to reduce inflammation and improve outcomes in chronic pancreatitis
Funded at Ohio State University · NIH-11260254 · Data updated 2026-11-12
This project gives people with chronic pancreatitis a soy-and-tomato drink to lower inflammation and help improve nutrition and symptoms.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Ohio State University NIH-funded |
| Lab location | 1 site (Columbus, UNITED STATES) |
| Project start | January 20, 2025 |
| Project end | November 30, 2027 |
| Funding year | 2026 |
| Award (this year) | $301,448 |
| NIH project number | 5R01DK138871-02 |
| Project ID | NIH-11260254 on NIH RePORTER |
Who could benefit from this research
✓Could help
People diagnosed with chronic pancreatitis who can drink the soy-tomato beverage and provide blood samples would be ideal candidates.
✕Less likely to help
People with soy or tomato allergies, or who cannot safely consume the drink, are unlikely to benefit from this project.
What this research studies
If you join, you'll drink a specially developed soy-tomato juice for a set period while researchers collect blood and health information. They will measure inflammatory markers, immune cell activity, and nutritional and metabolic outcomes to see whether inflammation falls. The team has already tested this soy-tomato juice in healthy volunteers and found it to be safe, tolerable, and absorbed into the body. The aim is to find a simple dietary approach that could reduce harmful inflammation and the complications of chronic pancreatitis.
Why it matters
Potential benefit: If successful, this dietary drink could reduce inflammation, improve nutritional health, and lower complications for people with chronic pancreatitis.
How similar studies have gone: Previous small studies showed the soy-tomato drink was safe and affected blood markers in healthy volunteers, but testing its effects in chronic pancreatitis is a new step.
Where this research is happening
-
Ohio State University
Columbus, United States Active
Researchers
- Principal investigator: Mace, Thomas a — Ohio State University
- Study coordinator: Mace, Thomas a
Related research
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A Cedars-Sinai research center is renewing its program to study chronic pancreatitis, diabetes-related pancreatic disease, and pancreatic cancer so doctors can better understand and treat these conditions.
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UPMC Center for Pancreatitis and Diabetes research program
A specialized center at the University of Pittsburgh is advancing clinical and biological studies of chronic pancreatitis, recurrent acute pancreatitis, and diabetes to improve understanding and care.
-
Chronic Pancreatitis Research Network to Understand Symptoms and Find Treatments
This project advances studies of chronic pancreatitis to understand why some people progress and to test new ideas that could diagnose or slow the disease.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.