Exploring the role of gut microbiome in gallstone disease

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to investigate the relationship between the gut microbiome and gallstone disease complications, such as pancreatitis and acute cholecystitis. Participants will provide stool samples at various time points, including before and after cholecystectomy, to assess changes in their gut microbiome. The study will involve 75 adult patients diagnosed with gallstone disease at East Kent University Hospitals NHS Foundation Trust. Data will be collected from electronic patient records to evaluate patient outcomes related to gallstone disease.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* All adults (age \>18 years of age) patients diagnosed with gallstone disease following confirmatory imaging at an East Kent University Foundation Trust Hospital. Patients of any gender, ethnicity or socio-economic background are eligible as well as pregnant women. Patients undergoing both open and laparoscopic cholecystectomy will be included.

Exclusion Criteria:

* Patients less than 18 years of age and patients who do not have capacity to consent to involvement in the study.

Where it's running

• Ekhuft
  Ashford, Kent, United Kingdom Recruiting

Study contacts

• Study coordinator: Charlotte Burford
• Email: charlotte.burford1@nhs.net
• Phone: +44 1227 766877

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.