NIH-funded research R01 grant

Internet-delivered pain self-management for pancreatitis

Official title: Internet-Delivered Pain Self-Management to Reduce Pain and Interference in Chronic Pancreatitis

Funded at Seattle Children's Hospital · NIH-11398838 · Data updated 2026-11-12

A digital cognitive-behavioral therapy program helps people with recurrent acute or chronic pancreatitis reduce pain and how much it interferes with daily life.

More Self-management research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionSeattle Children's Hospital
NIH-funded
Lab location1 site (Seattle, United States)
Project startSeptember 1, 2023
Project endJuly 31, 2028
Funding year2026
Award (this year)$697,377
NIH project number5R01DK137520-04
Project IDNIH-11398838 on NIH RePORTER

Who could benefit from this research

Could help

Adults with recurrent acute or chronic pancreatitis experiencing significant pain.

Less likely to help

Patients whose pain is not primarily influenced by psychosocial factors or who have barriers to internet-based therapy may receive limited benefit.

What this research studies

People with pancreatitis often suffer from severe abdominal pain that disrupts daily activities and leads to mood and sleep problems. This project tests an online, therapist-guided CBT course designed specifically for pancreatitis pain to lessen pain and improve functioning. It uses a hybrid design to measure how well the program works and how easily it can be put into real-world care. If successful, the program could be rapidly adopted in clinics treating pancreatitis patients.

Why it matters

Potential benefit: If effective, patients may experience less pain and better daily functioning with fewer opioid-related risks.

How similar studies have gone: Prior internet CBT for chronic pain has shown reductions in pain and disability, with promising but specific results for pancreatitis pain.

Where this research is happening

  • Seattle Children's Hospital
    Seattle, United States
    Active

Researchers

  • Principal investigator: Palermo, Tonya M — Seattle Children's Hospital
  • Study coordinator: Palermo, Tonya M

Related research

Other NIH-funded projects on the same topics.

  • Online pain self-management for pancreatitis

    An online cognitive-behavioral therapy program to help people with recurrent acute or chronic pancreatitis reduce pain and its effects on daily life.

    NIH research Seattle Children's Hospital · Seattle, United States · NIH-11164784

  • Online program to help manage pain in chronic pancreatitis patients

    This study is testing an online therapy program to help people with chronic pancreatitis manage their pain and improve their mood and daily life, and it's looking for participants who want to see if this approach works well in real life.

    NIH research Seattle Children's Hospital · Seattle, United States · NIH-10916518

  • Chronic Pancreatitis and Related Conditions Data Center Supports Multi-Center Research

    A national effort to organize and share clinical data and biosamples from people with chronic pancreatitis, pancreatogenic diabetes, and pancreatic cancer to speed biomarker discovery and new treatments.

    NIH research University of Tx Md Anderson Can Ctr · Houston, United States · NIH-11592146

  • Malabsorption Blood Test for Exocrine Pancreatic Function in Chronic Pancreatitis

    A blood test (MBT) will help identify people with mild to moderate pancreatic fat malabsorption and show how well enzyme therapy improves their quality of life.

    NIH research University of Pittsburgh at Pittsburgh · Pittsburgh, United States · NIH-11415052

  • Chronic Pancreatitis Clinical Research Cohort and Biorepository

    A long-term study at UF/Advent Health following adults with acute, relapsing, and chronic pancreatitis to build a detailed group with biospecimens and data for better diagnosis and personalized care.

    NIH research University of Florida · Gainesville, United States · NIH-11408761

  • Cedars-Sinai Center leads research on chronic pancreatitis and pancreatic cancer

    A Cedars-Sinai research center is renewing its program to study chronic pancreatitis, diabetes-related pancreatic disease, and pancreatic cancer so doctors can better understand and treat these conditions.

    NIH research Cedars-Sinai Medical Center · Los Angeles, United States · NIH-11401819

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.