Understanding how acute pancreatitis may lead to type 1 diabetes
Official title: Data Coordinating Center for the Type 1 Diabetes in Acute Pancreatitis Consortium
Funded at Pennsylvania State Univ Hershey Med Ctr · NIH-11324799 · Data updated 2026-11-12
This study is looking at how having acute pancreatitis might lead to type 1 diabetes, and it aims to find early warning signs and risk factors to help identify people who could be at risk for developing diabetes after pancreatitis.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Pennsylvania State Univ Hershey Med Ctr NIH-funded |
| Lab location | 1 site (Hershey, United States) |
| Project start | September 17, 2020 |
| Project end | July 31, 2025 |
| Funding year | 2025 |
| Award (this year) | $600,000 |
| NIH project number | 3U01DK127384-05S1 |
| Project ID | NIH-11324799 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals who have had episodes of acute pancreatitis and may be at risk for developing type 1 diabetes.
✕Less likely to help
Patients who have not experienced acute pancreatitis or do not have a risk of developing type 1 diabetes may not benefit from this research.
What this research studies
This research investigates the connection between acute pancreatitis and the development of type 1 diabetes mellitus (T1D). It aims to identify early biomarkers, clinical signs, and genetic risk factors that could indicate who is most at risk for developing T1D after experiencing acute pancreatitis. The study will involve collaboration among multiple clinical centers and will utilize a Data Coordinating Center to analyze data and support the research efforts. By understanding these relationships, the research seeks to inform better treatment practices and potentially reduce the incidence of T1D onset.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for preventing type 1 diabetes in patients who have experienced acute pancreatitis.
How similar studies have gone: Previous research has shown promising results in understanding the links between autoimmune conditions and acute pancreatitis, suggesting that this approach could yield valuable insights.
Where this research is happening
-
Pennsylvania State Univ Hershey Med Ctr
Hershey, United States Active
Researchers
- Principal investigator: Chinchilli, Vernon M — Pennsylvania State Univ Hershey Med Ctr
- Study coordinator: Chinchilli, Vernon M
Related research
Other NIH-funded projects on the same topics.
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Continuation of Type 1 Diabetes in Acute Pancreatitis: UF Health and AdventHealth
A patient-facing overview of a long-term study tracking people with acute pancreatitis to understand how some develop type 1 diabetes later and what factors influence that process.
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Data Coordinating Center for Type 1 Diabetes in Acute Pancreatitis Consortium
A national effort to learn how pancreatitis-related Type 1 diabetes develops, by tracking patients and coordinating data to improve future care.
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Type 1 Diabetes in Acute Pancreatitis in Diabetes Patients at Stanford
A Stanford-led project helps people with brittle type 1 diabetes who also experience pancreatitis by following them in a long-term study to understand how acute pancreatitis affects diabetes.
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Type 1 Diabetes after Acute Pancreatitis: Immune Clues from the Pacific Northwest
A multi-center study follows adults after an acute pancreatitis episode to understand how some develop Type 1 diabetes and what immune factors are involved.
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Diabetes After Acute Pancreatitis: Understanding Progression and Genetics at Cedars-Sinai
This grant supports Cedars-Sinai’s clinical center as part of a national effort to study why some adults develop brittle type 1 diabetes after an acute pancreatitis episode and how genes influence this risk.
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Cedars‑Sinai program on diabetes that follows acute pancreatitis
This program follows people who had acute pancreatitis to find biological and genetic signs that predict who will develop diabetes afterward.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.