Epidemiology and causes of diabetes after acute pancreatitis
Official title: Epidemiology and Pathophysiology of Acute Pancreatitis-related Diabetes Mellitus
Funded at Ohio State University · NIH-11413812 · Data updated 2026-11-12
A long-term study following people who have had acute pancreatitis to understand how often diabetes develops, why it happens, and how it progresses.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Ohio State University NIH-funded |
| Lab location | 1 site (Columbus, UNITED STATES) |
| Project start | September 17, 2020 |
| Project end | July 31, 2030 |
| Funding year | 2026 |
| Award (this year) | $520,000 |
| NIH project number | 5U01DK127388-07 |
| Project ID | NIH-11413812 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults with a history of acute pancreatitis who are enrolled in or eligible for the DREAM/T1DAPC cohorts and consenting to follow-up.
✕Less likely to help
People without a history of acute pancreatitis are unlikely to benefit from this specific study.
What this research studies
This project continues a national effort to track people with acute pancreatitis over time, checking their blood sugar and health outcomes at multiple visits. Researchers from several specialties will integrate clinical data, imaging, and nutrition information to uncover links between pancreatitis and diabetes. The study aims to identify who is at highest risk and what biological pathways contribute to AP-related diabetes, so that future prevention and treatment strategies can be developed. Participation would involve follow-up visits and sharing medical information as part of the DREAM cohorts led by the T1DAPC. The Ohio State University Clinical Center will help coordinate this multi-center effort and collaborate with other sites to advance understanding of this condition.
Why it matters
Potential benefit: If successful, the findings could improve early identification of people at risk for AP-related diabetes and guide better prevention and management strategies.
How similar studies have gone: Prior prospective cohorts have shown links between pancreatitis and subsequent diabetes, supporting the potential for meaningful insights in this project.
Where this research is happening
-
Ohio State University
Columbus, United States Active
Researchers
- Principal investigator: Papachristou, Georgios I — Ohio State University
- Study coordinator: Papachristou, Georgios I
Related research
Other NIH-funded projects on the same topics.
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Diabetes that develops after acute pancreatitis
This project follows people who've had acute pancreatitis to find out why and how often they develop diabetes.
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Understanding diabetes that develops after acute pancreatitis
This study is looking at how having a sudden inflammation of the pancreas, called acute pancreatitis, might lead to diabetes later on, and it’s for people who have experienced this condition to help find better ways to prevent and treat diabetes.
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Diabetes after acute pancreatitis: understanding and tracking progression
A patient-focused look at how diabetes can develop after an episode of acute pancreatitis, using data from a large, ongoing study and AI insights.
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Continuation of Type 1 Diabetes in Acute Pancreatitis: UF Health and AdventHealth
A patient-facing overview of a long-term study tracking people with acute pancreatitis to understand how some develop type 1 diabetes later and what factors influence that process.
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Data Coordinating Center for Type 1 Diabetes in Acute Pancreatitis Consortium
A national effort to learn how pancreatitis-related Type 1 diabetes develops, by tracking patients and coordinating data to improve future care.
-
Diabetes after acute pancreatitis: a patient-focused network study
A program at Indiana University is studying how diabetes can develop after an acute pancreatitis episode, with new findings that could help doctors tailor care for adults who had pancreatitis.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.