Chronic Pancreatitis Clinical Research Cohort and Biorepository
Official title: The Chronic Pancreatitis Clinical Research Consortium
Funded at University of Florida · NIH-11408761 · Data updated 2026-11-12
A long-term study at UF/Advent Health following adults with acute, relapsing, and chronic pancreatitis to build a detailed group with biospecimens and data for better diagnosis and personalized care.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Florida NIH-funded |
| Lab location | 1 site (Gainesville, United States) |
| Project start | September 1, 2025 |
| Project end | June 30, 2030 |
| Funding year | 2026 |
| Award (this year) | $404,327 |
| NIH project number | 5U01DK144420-02 |
| Project ID | NIH-11408761 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults 21 years and older with acute, relapsing acute, or chronic pancreatitis who are part of the PROCEED cohort or eligible for enrollment at participating sites.
✕Less likely to help
Patients not belonging to the PROCEED cohort or not undergoing pancreatitis-related care may not directly benefit from this repository-driven study.
What this research studies
This project continues the PROCEED cohort to recruit and monitor adults with acute, relapsing acute, and chronic pancreatitis. Researchers will collect blood, pancreatic and duodenal juice, urine, stool, saliva, and, when possible, pancreatic tissue, plus imaging and clinical data, to create a richly annotated biospecimen repository. The goal is to identify biomarkers that help with risk prediction, early diagnosis, prognosis, and tailoring treatments to individual patients. The work is designed to enable future studies on mechanisms and therapies to reduce pain, prevent relapses, and address related complications. Participation would involve periodic follow-up visits and providing samples as part of ongoing care at UF and affiliate sites.
Why it matters
Potential benefit: If successful, patients could benefit from earlier and more accurate diagnosis, better risk stratification, and more personalized treatment strategies for pancreatitis and its sequelae.
How similar studies have gone: Previous pancreatitis cohorts and biorepositories have advanced biomarker discovery and risk modeling, supporting the potential for meaningful findings in this approach.
Where this research is happening
-
University of Florida
Gainesville, United States Active
Researchers
- Principal investigator: Forsmark, Christopher E — University of Florida
- Study coordinator: Forsmark, Christopher E
Related research
Other NIH-funded projects on the same topics.
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Chronic Pancreatitis and Related Conditions Data Center Supports Multi-Center Research
A national effort to organize and share clinical data and biosamples from people with chronic pancreatitis, pancreatogenic diabetes, and pancreatic cancer to speed biomarker discovery and new treatments.
-
Malabsorption Blood Test for Exocrine Pancreatic Function in Chronic Pancreatitis
A blood test (MBT) will help identify people with mild to moderate pancreatic fat malabsorption and show how well enzyme therapy improves their quality of life.
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Cedars-Sinai Center leads research on chronic pancreatitis and pancreatic cancer
A Cedars-Sinai research center is renewing its program to study chronic pancreatitis, diabetes-related pancreatic disease, and pancreatic cancer so doctors can better understand and treat these conditions.
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UPMC Center for Pancreatitis and Diabetes research program
A specialized center at the University of Pittsburgh is advancing clinical and biological studies of chronic pancreatitis, recurrent acute pancreatitis, and diabetes to improve understanding and care.
-
Chronic Pancreatitis Research Network to Understand Symptoms and Find Treatments
This project advances studies of chronic pancreatitis to understand why some people progress and to test new ideas that could diagnose or slow the disease.
-
Chronic Pancreatitis Clinical Research Consortium at Stanford
A Stanford-based effort is renewing a patient-centered program to study chronic pancreatitis and recurrent acute pancreatitis, with ongoing recruitment of both adult and pediatric participants.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.