Registry for patients with pancreatic diseases
Pancreas Disease and High Risk Registry
This study is creating a registry to collect information from patients with pancreatic diseases to help researchers understand what causes these conditions and how to prevent them.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 1368 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Icahn School of Medicine at Mount Sinai Academic / other |
| Locations | 2 sites (New York, New York and 1 other locations) |
| Trial ID | NCT02775461 on ClinicalTrials.gov |
What this trial studies
This project aims to establish a comprehensive registry of patients diagnosed with various pancreatic diseases, including pancreatic cancer, precancerous lesions, and chronic pancreatitis. The registry will collect detailed data on personal and family medical histories, demographics, and risk factors to better understand the development of pancreatic cancer and related conditions. By gathering this information, researchers hope to identify patterns and risk factors that contribute to pancreatic diseases, ultimately aiding in prevention and prognosis efforts.
Who should consider this trial
Good fit: Ideal candidates for this registry include individuals with a family history of pancreatic cancer, specific genetic mutations associated with increased risk, or those with pancreatic cysts measuring 1 cm or larger.
Not a fit: Patients who do not have a family history of pancreatic cancer or related genetic predispositions may not benefit from this registry.
Why it matters
Potential benefit: If successful, this registry could lead to improved understanding and management of pancreatic diseases, potentially enhancing early detection and prevention strategies for patients at risk.
How similar studies have performed: While this registry approach is not novel, it builds on previous efforts to understand pancreatic diseases, which have shown promise in identifying risk factors and improving patient outcomes.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * At least 1 first degree relative affected with Pancreatic Cancer * Any of (BRCA1, BRCA2, PALB2, ATM) mutations + 1 family member with Pancreatic Cancer * mFAMMM (p16,CDKN2A mutations) + 1 family member with Pancreatic cancer * Known mutation carrier for STK11 (Peutz Jeghers Syndrome) * Lynch syndrome (HNPCC) + 1 family PDAC * Known mutation carrier for Hereditary pancreatitis * Individuals with a history of pancreatic cyst(s) (IPMN's) that measure ≥ 1 cm Exclusion Criteria: * Patients who do not speak English or Spanish * Refusal by patient * Individuals under the age of 18 years
Where this trial is running
New York, New York and 1 other locations
- Mount Sinai West — New York, New York, United States (Recruiting)
- Icahn School of Medicine at Mount Sinai — New York, New York, United States (Recruiting)
Study contacts
- Principal investigator: Aimee Lucas, MD, MS — Icahn School of Medicine at Mount Sinai
- Study coordinator: Joyce Serebrenik
- Email: joyce.serebrenik@mountsinai.org
- Phone: (212) 241-7269
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.