OKPRC: Improving diagnosis and care for chronic pancreatitis
Official title: Ohio Kentucky Pancreatitis Research Center (OKPRC) to advance the diagnosis and treatment of chronic pancreatitis
Funded at Ohio State University · NIH-11400442 · Data updated 2026-11-12
A program from Ohio State University aims to improve how chronic pancreatitis is diagnosed and treated, through biomarker validation, nutrition research, and clinical trials.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Ohio State University NIH-funded |
| Lab location | 1 site (Columbus, UNITED STATES) |
| Project start | September 1, 2025 |
| Project end | June 30, 2030 |
| Funding year | 2026 |
| Award (this year) | $620,223 |
| NIH project number | 5U01DK144496-02 |
| Project ID | NIH-11400442 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults with chronic pancreatitis who may participate in biomarker validation, nutritional analyses, or related clinical trials.
✕Less likely to help
Participants not meeting the study criteria or not eligible for specific trials may not directly benefit, though findings could still inform future care.
What this research studies
If you have chronic pancreatitis, this grant supports a center-led effort to understand the disease better and accelerate better care. It plans a biomarker study to help diagnose the condition more accurately, explore how nutrition and diet relate to disease progression, and advance clinical trials for new treatments. The work would involve longitudinal clinical research with participants to validate findings and test potential interventions. The center will build infrastructure and collaborate across sites to address gaps in knowledge about chronic pancreatitis.
Why it matters
Potential benefit: It could lead to faster, more accurate diagnosis and new ways to manage and treat chronic pancreatitis.
How similar studies have gone: Previous biomarker and nutritional studies in chronic pancreatitis have shown promise but require validation in larger cohorts.
Where this research is happening
-
Ohio State University
Columbus, United States Active
Researchers
- Principal investigator: Hart, Philip a. — Ohio State University
- Study coordinator: Hart, Philip a.
Related research
Other NIH-funded projects on the same topics.
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Chronic Pancreatitis and Related Conditions Data Center Supports Multi-Center Research
A national effort to organize and share clinical data and biosamples from people with chronic pancreatitis, pancreatogenic diabetes, and pancreatic cancer to speed biomarker discovery and new treatments.
-
Malabsorption Blood Test for Exocrine Pancreatic Function in Chronic Pancreatitis
A blood test (MBT) will help identify people with mild to moderate pancreatic fat malabsorption and show how well enzyme therapy improves their quality of life.
-
Chronic Pancreatitis Clinical Research Cohort and Biorepository
A long-term study at UF/Advent Health following adults with acute, relapsing, and chronic pancreatitis to build a detailed group with biospecimens and data for better diagnosis and personalized care.
-
Cedars-Sinai Center leads research on chronic pancreatitis and pancreatic cancer
A Cedars-Sinai research center is renewing its program to study chronic pancreatitis, diabetes-related pancreatic disease, and pancreatic cancer so doctors can better understand and treat these conditions.
-
UPMC Center for Pancreatitis and Diabetes research program
A specialized center at the University of Pittsburgh is advancing clinical and biological studies of chronic pancreatitis, recurrent acute pancreatitis, and diabetes to improve understanding and care.
-
Chronic Pancreatitis Research Network to Understand Symptoms and Find Treatments
This project advances studies of chronic pancreatitis to understand why some people progress and to test new ideas that could diagnose or slow the disease.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.