Condition

Acute Liver Failure clinical trials and research

• 6Clinical trials
• 16Countries

Newest Acute Liver Failure clinical trials

All recruiting trials (6)

• N-acetylcysteine for non-acetaminophen-induced acute liver failure

  Researchers are testing whether adding oral N-acetylcysteine to standard care helps adults with non-acetaminophen acute liver failure survive longer compared with standard care alone.

  Recruiting King Edward Medical University · Lahore, Punjab Province · NCT07765823

• Reference framework for outcomes after machine-preserved liver transplantation in Europe

  This study tests how liver transplants that use machine perfusion perform in real-world practice, to see how different perfusion methods relate to outcomes for adults in Europe.

  Recruiting at 4 sites University Medical Center Groningen · Innsbruck and 37 other locations · NCT07585890

• Combined DPMAS (double plasma molecular adsorption) and therapeutic plasma exchange to improve clotting, reduce inflammation, and support organs in acute liver failure

  We will test whether combining DPMAS (double plasma molecular adsorption) with therapeutic plasma exchange (TPE) helps adults in the ICU with acute liver failure or acute-on-chronic liver failure recover organ function or safely reach a transplant.

  Recruiting Institute for Clinical and Experimental Medicine · Prague · NCT07329036

• Standard-volume versus high-volume plasma exchange for children with acute liver failure

  This trial will see if using high-volume plasma exchange instead of standard-volume plasma exchange helps children (ages 3–18) with acute liver failure keep their native liver.

  Recruiting Institute of Liver and Biliary Sciences, India · New Delhi, National Capital Territory of Delhi · NCT06831643

• F573 injection for treating liver injury and failure

  This study is testing if an injection called F573 can help people with liver injury or chronic hepatitis B feel better and recover.

  Recruiting at 10 sites Phase 2 Beijing Continent Pharmaceutical Co, Ltd. · Beijing, Beijing Municipality and 9 other locations · NCT05689645

• Registry for monitoring CytoSorb device use in critically ill patients

  This study is collecting information on how the CytoSorb device helps critically ill patients to improve care for conditions like septic shock and acute respiratory distress syndrome.

  Recruiting at 24 sites CytoSorbents, Inc · Klagenfurt and 27 other locations · NCT05146336

Related topics

Quick answers

How many Acute Liver Failure clinical trials are recruiting right now?

6, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 16 countries. The most sites are in Austria (2 trials), Germany (2 trials), Italy (2 trials), Spain (2 trials), Pakistan (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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