Diabetes after acute pancreatitis: a patient-focused network study
Official title: Indiana University clinical Center for acute pancreatitis and diabetes clinical research network
Funded at Indiana University Indianapolis · NIH-11416481 · Data updated 2026-11-12
A program at Indiana University is studying how diabetes can develop after an acute pancreatitis episode, with new findings that could help doctors tailor care for adults who had pancreatitis.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Indiana University Indianapolis NIH-funded |
| Lab location | 1 site (Indianapolis, United States) |
| Project start | September 17, 2020 |
| Project end | July 31, 2030 |
| Funding year | 2026 |
| Award (this year) | $504,541 |
| NIH project number | 5U01DK127382-07 |
| Project ID | NIH-11416481 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults who recently experienced acute pancreatitis and are at risk for or developing diabetes.
✕Less likely to help
People without a recent pancreatitis history or diabetes may not benefit directly.
What this research studies
This project follows adults who recently had acute pancreatitis to understand why some develop diabetes and how autoimmune processes, beta cell function, and insulin resistance relate to that outcome. It collects clinical data, blood samples, and imaging over time to map immune activity and changes in the pancreas. The study aims to create clearer pathways for diagnosis and management of diabetes that emerges after pancreatitis, using real-world observations from multiple centers. Participants would be involved in ongoing follow-up visits and biospecimen collection as part of a national consortium.
Why it matters
Potential benefit: If successful, it could lead to earlier detection and personalized treatment for diabetes that develops after pancreatitis.
How similar studies have gone: The DREAM study within the consortium has shown that post-pancreatitis diabetes is identifiable through targeted biomarkers and imaging.
Where this research is happening
-
Indiana University Indianapolis
Indianapolis, United States Active
Researchers
- Principal investigator: Fogel, Evan L — Indiana University Indianapolis
- Study coordinator: Fogel, Evan L
Related research
Other NIH-funded projects on the same topics.
-
Diabetes after acute pancreatitis: understanding and tracking progression
A patient-focused look at how diabetes can develop after an episode of acute pancreatitis, using data from a large, ongoing study and AI insights.
-
Continuation of Type 1 Diabetes in Acute Pancreatitis: UF Health and AdventHealth
A patient-facing overview of a long-term study tracking people with acute pancreatitis to understand how some develop type 1 diabetes later and what factors influence that process.
-
Data Coordinating Center for Type 1 Diabetes in Acute Pancreatitis Consortium
A national effort to learn how pancreatitis-related Type 1 diabetes develops, by tracking patients and coordinating data to improve future care.
-
Type 1 Diabetes in Acute Pancreatitis in Diabetes Patients at Stanford
A Stanford-led project helps people with brittle type 1 diabetes who also experience pancreatitis by following them in a long-term study to understand how acute pancreatitis affects diabetes.
-
Epidemiology and causes of diabetes after acute pancreatitis
A long-term study following people who have had acute pancreatitis to understand how often diabetes develops, why it happens, and how it progresses.
-
Type 1 Diabetes after Acute Pancreatitis: Immune Clues from the Pacific Northwest
A multi-center study follows adults after an acute pancreatitis episode to understand how some develop Type 1 diabetes and what immune factors are involved.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.