Diabetes after acute pancreatitis: monitoring blood sugar with continuous glucose sensors
Diabetes RElated to Acute Pancreatitis and its Mechanisms: Metabolic Outcomes Using Novel CGM Metrics (DREAM-ON)
This project uses wearable continuous glucose monitors to track blood sugar patterns in adults who have had acute pancreatitis to better understand who develops diabetes.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Pennsylvania State Univ Hershey Med Ctr NIH-funded |
| Lab location | 1 site (Hershey, United States) |
| Project ID | NIH-11326762 on NIH RePORTER |
What this research studies
You would be followed after an episode of acute pancreatitis and asked to wear a continuous glucose monitor (CGM) so researchers can see detailed blood sugar patterns over time. The study is part of a larger observational consortium that collects clinical data, blood tests, and measures of beta cell function, insulin resistance, and immune markers. Researchers will combine CGM metrics with lab results and patient histories to look for early signs and mechanisms of diabetes after pancreatitis. Participation may involve clinic visits, blood draws, and active follow-up for months to years.
Who could benefit from this research
Good fit: Adults (age 21+) who have experienced one or more episodes of acute pancreatitis and are willing to attend follow-up visits, wear a CGM, and provide blood samples.
Not a fit: People without a history of acute pancreatitis, children, or those with long-standing insulin-dependent diabetes are unlikely to benefit directly from this study.
Why it matters
Potential benefit: If successful, this work could help identify who is at higher risk of developing diabetes after pancreatitis earlier and point to ways to prevent or better manage it.
How similar studies have performed: Previous observational studies and meta-analyses show increased diabetes risk after pancreatitis, but applying detailed CGM metrics to define mechanisms is a relatively new approach.
Where this research is happening
Hershey, United States
- Pennsylvania State Univ Hershey Med Ctr — Hershey, United States (Active)
Researchers
- Principal investigator: Chinchilli, Vernon M — Pennsylvania State Univ Hershey Med Ctr
- Study coordinator: Chinchilli, Vernon M
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.