Diabetes After Acute Pancreatitis: Understanding Progression and Genetics at Cedars-Sinai
Official title: Cedars Sinai Clinical Center of the Type 1 Diabetes in Acute Pancreatitis Consortium
Funded at Cedars-Sinai Medical Center · NIH-11413637 · Data updated 2026-11-12
This grant supports Cedars-Sinai’s clinical center as part of a national effort to study why some adults develop brittle type 1 diabetes after an acute pancreatitis episode and how genes influence this risk.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Cedars-Sinai Medical Center NIH-funded |
| Lab location | 1 site (Los Angeles, United States) |
| Project start | September 16, 2020 |
| Project end | July 31, 2030 |
| Funding year | 2026 |
| Award (this year) | $511,000 |
| NIH project number | 5U01DK127403-07 |
| Project ID | NIH-11413637 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults with brittle diabetes or a history of acute pancreatitis who may participate in long-term follow-up and biomarker studies.
✕Less likely to help
Individuals without a history of pancreatitis or brittle diabetes may not directly benefit from this specific program.
What this research studies
If you have adult-onset brittle diabetes or have had acute pancreatitis, this program aims to follow patients over time to understand who may develop ongoing diabetes and what biological pathways are involved. The team will continue enrolling participants, keeping them engaged, and collecting data and samples to study progression. They also plan to investigate genetic factors that might make certain people more likely to develop diabetes after pancreatitis and to explore biomarkers that signal progression. The work focuses on translating findings into better risk prediction and potential future treatments for those affected. This is a renewal of Cedars-Sinai’s role in the DREAM study and its ancillary projects.
Why it matters
Potential benefit: Better understanding of who is at risk for persistent diabetes after pancreatitis could lead to earlier interventions and more personalized care.
How similar studies have gone: The DREAM study and related ancillary studies have shown progress in recruitment and identifying pathways, with ongoing efforts to refine biomarkers.
Where this research is happening
-
Cedars-Sinai Medical Center
Los Angeles, United States Active
Researchers
- Principal investigator: Goodarzi, Mark — Cedars-Sinai Medical Center
- Study coordinator: Goodarzi, Mark
Related research
Other NIH-funded projects on the same topics.
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Continuation of Type 1 Diabetes in Acute Pancreatitis: UF Health and AdventHealth
A patient-facing overview of a long-term study tracking people with acute pancreatitis to understand how some develop type 1 diabetes later and what factors influence that process.
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Data Coordinating Center for Type 1 Diabetes in Acute Pancreatitis Consortium
A national effort to learn how pancreatitis-related Type 1 diabetes develops, by tracking patients and coordinating data to improve future care.
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Type 1 Diabetes in Acute Pancreatitis in Diabetes Patients at Stanford
A Stanford-led project helps people with brittle type 1 diabetes who also experience pancreatitis by following them in a long-term study to understand how acute pancreatitis affects diabetes.
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Type 1 Diabetes after Acute Pancreatitis: Immune Clues from the Pacific Northwest
A multi-center study follows adults after an acute pancreatitis episode to understand how some develop Type 1 diabetes and what immune factors are involved.
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Understanding how acute pancreatitis may lead to type 1 diabetes
This study is looking at how having acute pancreatitis might lead to type 1 diabetes, and it aims to find early warning signs and risk factors to help identify people who could be at risk for developing diabetes after pancreatitis.
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Cedars‑Sinai program on diabetes that follows acute pancreatitis
This program follows people who had acute pancreatitis to find biological and genetic signs that predict who will develop diabetes afterward.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.