Examining joint motion problems in stroke patients and healthy volunteers

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to evaluate the reliability of a standardized physical examination method for identifying motion problems in joints among adults, including those hospitalized with stroke or transient ischemic attack (TIA). The study will assess whether different healthcare providers can consistently quantify motion pattern issues using the Functional Pathology of the Musculoskeletal System (FPMSS) model. It will also explore differences in joint motion patterns between asymptomatic individuals and those with stroke or TIA, as well as the relationship between joint motion impairment severity and outcomes for stroke survivors.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* adults ≥18 years

Admission diagnosis:

* ischemic stroke OR
* transient ischemic attack (TIA). A prior history of TIA but without stroke may be enrolled.
* Neurologic stability or lack of significant deterioration (i.e. ∆ NIHSS\<4) for at least 24 hours (defined by clinical documentation and/or communication with provider team(s)) in stroke subjects
* Able to sit upright, lie supine, and when able lateral recumbent left/right positions with assist independently or with minimal person assist
* Anticipated length of stay greater \> or = 2 days for ischemic stroke. TIA patients average length of stay is \< 2 days, and can be enrolled in the study.

Exclusion Criteria:

* Acute skeletal fracture or known dislocation; history of pathologic (osteoporotic or neoplastic) skeletal fracture of thoracic cage, hip/pelvis/sacrum, or vertebral column
* Prior history of ICH, ischemic stroke, confirmed by imaging and/or clinical evaluation. Patients with imaging showing "chronic stroke" who have never received a diagnosis of stroke and/or have not been previously symptomatic may still be enrolled, based on the Investigator's clinical judgement.
* Spinal column support brace (e.g. cervical collar)
* Anticipated neurosurgical intervention during hospitalization: decompressive hemicraniectomy, hematoma evacuation (defined by clinical documentation and/or communication with provider team(s))
* Current endotracheal intubation (\*note: extubated patients can be evaluated for eligibility)
* History of spinal cord injury with residual neuromuscular or sensory disability
* History of recent trauma within the past 30 days
* Known ligament, musculotendinous, or bone lesion
* Clinical condition that would interfere with execution of movement or palpatory diagnostic testing, e.g. chronic pain
* History of spinal surgery

Where it's running

• University of California Davis Medical Center
  Sacramento, California, United States Recruiting

Study contacts

• Principal investigator: Alan Yee, D.O. — University of California, Davis
• Study coordinator: Alan Yee, D.O.
• Email: ahyee@ucdavis.edu
• Phone: 916-734-3588

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.