Rescue stenting and thrombolysis for large vessel ischemic stroke
Official title: Stroke, Thrombolysis and Rescue Stenting
Run by ASST Santi Paolo e Carlo · NCT06727006 · Data updated 2026-11-12
This study tests if combining rescue stenting with a clot-busting treatment can help adults who have a severe stroke and didn't get better with standard procedures.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 400 (estimated) |
| Sponsor | ASST Santi Paolo e Carlo Academic / other |
| Locations | 7 sites (Bergamo, Italy and 6 other locations) |
| Status | Recruiting |
| Started | October 21, 2023 |
| Main results expected | December 2026 |
| Study ends | March 2027 |
| Registry record updated | December 17, 2024 |
| Trial ID | NCT06727006 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults aged 18 and older with large vessel occlusion strokes undergoing thrombectomy and rescue stenting within 24 hours of symptom onset.
✕Probably not a fit
Patients under 18 years of age or those who refuse to give informed consent may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study investigates the use of rescue stenting in conjunction with intravenous thrombolysis for patients experiencing acute large vessel occlusion strokes. It aims to assess the effectiveness of rescue stenting as a treatment option for patients who do not achieve successful recanalization through standard thrombectomy methods. The study will include patients who are 18 years or older and have undergone thrombectomy and rescue stenting within 24 hours of stroke onset. The goal is to gather data on patient outcomes following these interventions.
Why it matters
Potential benefit: If successful, this approach could provide a new treatment option for patients with large vessel occlusion strokes who fail standard thrombectomy.
How similar studies have gone: While the use of rescue stenting has been suggested in expert consensus statements, this specific approach has not been extensively tested in prior studies.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients with large vessel occlusion strokes undergoing thrombectomy and rescue stenting within 24 hours of stroke onset * Patients ≥ 18 years of age Exclusion Criteria: * Patients \< 18 years * Refusal to give informed consent
Where it's running
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ASST Papa Giovanni XXIII
Bergamo, Italy, Italy Recruiting -
Ospedale Bufalini
Cesena, Italy, Italy Recruiting -
Azienda Sanitaria Lecce - Ospedale "Vito Fazzi"
Lecce, Italy, Italy Recruiting -
ASST Santi Paolo e Carlo
Milan, Italy, Italy Recruiting -
ASST Grande Ospedale Metropolitano Niguarda
Milan, Italy, Italy Recruiting -
Fondazione IRCCS San Gerardo dei Tintori
Monza, Italy, Italy Recruiting
Show 1 more location
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ASL 2 Savonese - Ospedale Santa Corona
Pietra Ligure, Italy, Italy Recruiting
Study contacts
- Principal investigator: Elena Ballabio, MD — ASST Santi Paolo e Carlo
- Study coordinator: Elena Ballabio, Medical Doctor
- Email: elena.ballabio@asst-santipaolocarlo.it
- Phone: +393470772687
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.