Clinical trial Recruiting at 7 sites Observational Ages 18 and up

Rescue stenting and thrombolysis for large vessel ischemic stroke

Official title: Stroke, Thrombolysis and Rescue Stenting

Run by ASST Santi Paolo e Carlo · NCT06727006 · Data updated 2026-11-12

This study tests if combining rescue stenting with a clot-busting treatment can help adults who have a severe stroke and didn't get better with standard procedures.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment400 (estimated)
SponsorASST Santi Paolo e Carlo
Academic / other
Locations7 sites (Bergamo, Italy and 6 other locations)
StatusRecruiting
StartedOctober 21, 2023
Main results expectedDecember 2026
Study endsMarch 2027
Registry record updatedDecember 17, 2024
Trial IDNCT06727006 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults aged 18 and older with large vessel occlusion strokes undergoing thrombectomy and rescue stenting within 24 hours of symptom onset.

Probably not a fit

Patients under 18 years of age or those who refuse to give informed consent may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the use of rescue stenting in conjunction with intravenous thrombolysis for patients experiencing acute large vessel occlusion strokes. It aims to assess the effectiveness of rescue stenting as a treatment option for patients who do not achieve successful recanalization through standard thrombectomy methods. The study will include patients who are 18 years or older and have undergone thrombectomy and rescue stenting within 24 hours of stroke onset. The goal is to gather data on patient outcomes following these interventions.

Why it matters

Potential benefit: If successful, this approach could provide a new treatment option for patients with large vessel occlusion strokes who fail standard thrombectomy.

How similar studies have gone: While the use of rescue stenting has been suggested in expert consensus statements, this specific approach has not been extensively tested in prior studies.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients with large vessel occlusion strokes undergoing thrombectomy and rescue stenting within 24 hours of stroke onset
* Patients ≥ 18 years of age

Exclusion Criteria:

* Patients \< 18 years
* Refusal to give informed consent

Where it's running

  • ASST Papa Giovanni XXIII
    Bergamo, Italy, Italy
    Recruiting
  • Ospedale Bufalini
    Cesena, Italy, Italy
    Recruiting
  • Azienda Sanitaria Lecce - Ospedale "Vito Fazzi"
    Lecce, Italy, Italy
    Recruiting
  • ASST Santi Paolo e Carlo
    Milan, Italy, Italy
    Recruiting
  • ASST Grande Ospedale Metropolitano Niguarda
    Milan, Italy, Italy
    Recruiting
  • Fondazione IRCCS San Gerardo dei Tintori
    Monza, Italy, Italy
    Recruiting
Show 1 more location
  • ASL 2 Savonese - Ospedale Santa Corona
    Pietra Ligure, Italy, Italy
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.