Rescue stenting and thrombolysis for large vessel ischemic stroke
Stroke, Thrombolysis and Rescue Stenting
This study tests if combining rescue stenting with a clot-busting treatment can help adults who have a severe stroke and didn't get better with standard procedures.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 400 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | ASST Santi Paolo e Carlo Academic / other |
| Locations | 7 sites (Bergamo, Italy and 6 other locations) |
| Trial ID | NCT06727006 on ClinicalTrials.gov |
What this trial studies
This study investigates the use of rescue stenting in conjunction with intravenous thrombolysis for patients experiencing acute large vessel occlusion strokes. It aims to assess the effectiveness of rescue stenting as a treatment option for patients who do not achieve successful recanalization through standard thrombectomy methods. The study will include patients who are 18 years or older and have undergone thrombectomy and rescue stenting within 24 hours of stroke onset. The goal is to gather data on patient outcomes following these interventions.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18 and older with large vessel occlusion strokes undergoing thrombectomy and rescue stenting within 24 hours of symptom onset.
Not a fit: Patients under 18 years of age or those who refuse to give informed consent may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could provide a new treatment option for patients with large vessel occlusion strokes who fail standard thrombectomy.
How similar studies have performed: While the use of rescue stenting has been suggested in expert consensus statements, this specific approach has not been extensively tested in prior studies.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients with large vessel occlusion strokes undergoing thrombectomy and rescue stenting within 24 hours of stroke onset * Patients ≥ 18 years of age Exclusion Criteria: * Patients \< 18 years * Refusal to give informed consent
Where this trial is running
Bergamo, Italy and 6 other locations
- ASST Papa Giovanni XXIII — Bergamo, Italy, Italy (Recruiting)
- Ospedale Bufalini — Cesena, Italy, Italy (Recruiting)
- Azienda Sanitaria Lecce - Ospedale "Vito Fazzi" — Lecce, Italy, Italy (Recruiting)
- ASST Santi Paolo e Carlo — Milan, Italy, Italy (Recruiting)
- ASST Grande Ospedale Metropolitano Niguarda — Milan, Italy, Italy (Recruiting)
- Fondazione IRCCS San Gerardo dei Tintori — Monza, Italy, Italy (Recruiting)
- ASL 2 Savonese - Ospedale Santa Corona — Pietra Ligure, Italy, Italy (Recruiting)
Study contacts
- Principal investigator: Elena Ballabio, MD — ASST Santi Paolo e Carlo
- Study coordinator: Elena Ballabio, Medical Doctor
- Email: elena.ballabio@asst-santipaolocarlo.it
- Phone: +393470772687
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.