Analyzing non-coding RNA in patients with acute ischemic stroke undergoing endovascular treatment

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the expression patterns of circular RNA (circRNA), long non-coding RNA (lncRNA), and micro-RNA (miRNA) in patients with acute ischemic stroke who are treated with endovascular therapy. Using next-generation sequencing, the study aims to identify potential biomarkers and regulators that could indicate the progression and prognosis of the condition. Additionally, it will evaluate the impact of endovascular treatment on immune responses in these patients. The findings may lead to the development of predictive models for patient outcomes based on the identified non-coding RNAs.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Aged 18 years or older
* Confirmed acute ischemic stroke by a diffusion-weighted imaging-position lesion on magnetic resonance imaging (MRI) and a new lesion on a brain computed tomography (CT) scan
* Within 24 hours of symptom onset and treat with endovascular therapy
* Good performance status
* Signed an approved informed consents

Exclusion Criteria:

* a history of hemorrhagic infarction, chronic kidney/liver diseases, peripheral arterial occlusive disease, active malignant disease, and inflammatory or infectious diseases

Where it's running

• Nanjing First Hospital, Nanjing Medical University
  Nanjing, Jiangsu, China Recruiting

Study contacts

• Study coordinator: Junshan Zhou, M.D
• Email: zhjsh333@126.com
• Phone: +8602587726218

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.