Improving emergency evaluation and transfer protocols for stroke patients
Official title: Implementation of a Stroke Protocol for Emergency Evaluation and Disposition
Run by University of Chicago · NCT06094478 · Data updated 2026-11-12
This study is testing a new way to speed up the transfer of stroke patients to specialized hospitals to see if it helps them get better faster.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 900 (estimated) |
| Sponsor | University of Chicago Academic / other |
| Locations | 8 sites (New Haven, Connecticut and 7 other locations) |
| Status | Recruiting |
| Started | October 17, 2024 |
| Main results expected | January 31, 2028 |
| Study ends | July 31, 2028 |
| Registry record updated | May 20, 2026 |
| Trial ID | NCT06094478 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are adults aged 18 and older who have been diagnosed with acute ischemic stroke, intracerebral hemorrhage, or subarachnoid hemorrhage.
✕Probably not a fit
Patients who are under 18 years old, diagnosed with transient ischemic attack, or those receiving comfort care measures may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study aims to enhance the evaluation and transfer process for stroke patients who require advanced care at comprehensive stroke centers. By implementing a novel, evidence-based protocol called HI-SPEED across eight diverse stroke systems in the US, the study seeks to reduce the time it takes for patients to be transferred from non-comprehensive hospitals to those that can provide specialized treatment. The effectiveness of this intervention will be evaluated based on median transfer times and patient disability outcomes, while also assessing the quality of implementation. The study leverages interdisciplinary expertise in stroke care and aims to establish a model for widespread dissemination of improved protocols.
Why it matters
Potential benefit: If successful, this study could significantly reduce transfer times for stroke patients, leading to better treatment outcomes and reduced disability.
How similar studies have gone: Previous studies have shown success in implementing similar protocols to reduce transfer times and improve outcomes for stroke patients.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age \>=18 years * Final diagnosis: AIS, ICH, or SAH Exclusion Criteria: * Final diagnosis: TIA or stroke NOS * Age \<18 years * Comfort care measures on day 0 or 1 * Left hospital against medical advice * Enrolled in clinical trial related to stroke that is competing with this study
Where it's running
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Yale New Haven Hospital
New Haven, Connecticut, United States Recruiting -
Jackson Memorial Hospital
Miami, Florida, United States Recruiting -
Emory University Hospital
Atlanta, Georgia, United States Recruiting -
UChicago Medicine Ingalls Memorial Hospital
Chicago, Illinois, United States Recruiting -
University of Michigan Hospital
Ann Arbor, Michigan, United States Recruiting -
New York Presbyterian - Weill Cornell Hospital
New York, New York, United States Recruiting
Show 2 more locations
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University of Cincinnati Medical Center
Cincinnati, Ohio, United States Recruiting -
University of Utah Health
Salt Lake City, Utah, United States Recruiting
Study contacts
- Principal investigator: Shyam Prabhakaran, MD, MS — University of Chicago
- Study coordinator: Shyam Prabhakaran, MD, MS
- Email: shyam1@bsd.uchicago.edu
- Phone: 773-702-0080
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.