Improving emergency evaluation and transfer protocols for stroke patients

Implementation of a Stroke Protocol for Emergency Evaluation and Disposition

Not applicable Interventional University of Chicago · NCT06094478

This study is testing a new way to speed up the transfer of stroke patients to specialized hospitals to see if it helps them get better faster.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment900 (estimated)
Ages18 Years and up
SexAll
SponsorUniversity of Chicago Academic / other
Locations7 sites (New Haven, Connecticut and 6 other locations)
Trial IDNCT06094478 on ClinicalTrials.gov

What this trial studies

This study aims to enhance the evaluation and transfer process for stroke patients who require advanced care at comprehensive stroke centers. By implementing a novel, evidence-based protocol called HI-SPEED across eight diverse stroke systems in the US, the study seeks to reduce the time it takes for patients to be transferred from non-comprehensive hospitals to those that can provide specialized treatment. The effectiveness of this intervention will be evaluated based on median transfer times and patient disability outcomes, while also assessing the quality of implementation. The study leverages interdisciplinary expertise in stroke care and aims to establish a model for widespread dissemination of improved protocols.

Who should consider this trial

Good fit: Ideal candidates for this study are adults aged 18 and older who have been diagnosed with acute ischemic stroke, intracerebral hemorrhage, or subarachnoid hemorrhage.

Not a fit: Patients who are under 18 years old, diagnosed with transient ischemic attack, or those receiving comfort care measures may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could significantly reduce transfer times for stroke patients, leading to better treatment outcomes and reduced disability.

How similar studies have performed: Previous studies have shown success in implementing similar protocols to reduce transfer times and improve outcomes for stroke patients.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age \>=18 years
* Final diagnosis: AIS, ICH, or SAH

Exclusion Criteria:

* Final diagnosis: TIA or stroke NOS
* Age \<18 years
* Comfort care measures on day 0 or 1
* Left hospital against medical advice
* Enrolled in clinical trial related to stroke that is competing with this study

Where this trial is running

New Haven, Connecticut and 6 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Stroke, AcuteIschemic Stroke, AcuteHemorrhagic Strokeinterhospital transferquality improvementimplementation sciencestroke systems of care
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.