Bimanual motor skill learning for patients recovering from acute stroke
Exploring the Neural Substrates of Proximal and Distal Bimanual Motor Skill Learning Through Robotics and Multimodal Brain Imaging
This study tests how stroke affects learning to use both hands together and aims to find better ways to help patients recover their motor skills.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 160 (estimated) |
| Ages | 18 Years to 90 Years |
| Sex | All |
| Sponsor | University Hospital of Mont-Godinne Academic / other |
| Locations | 2 sites (Yvoir, Namur and 1 other locations) |
| Trial ID | NCT05760846 on ClinicalTrials.gov |
What this trial studies
This study investigates how acute stroke affects the ability to learn bimanual motor skills, which are essential for rehabilitation. Patients will participate in training sessions using specialized robotic devices and manual dexterity tools over three consecutive days. The research aims to identify the neural mechanisms involved in motor skill learning and how different brain lesions impact recovery. By analyzing performance in both proximal and distal bimanual tasks, the study seeks to enhance rehabilitation strategies for stroke patients.
Who should consider this trial
Good fit: Ideal candidates include adults aged 18-90 who have experienced an acute stroke within the last 21 days.
Not a fit: Patients with severe cognitive deficits, full paralysis of the arm, or multiple strokes may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved rehabilitation techniques that enhance motor recovery in stroke patients.
How similar studies have performed: While the approach of using robotic devices for motor skill learning in stroke rehabilitation has been explored, the specific focus on bimanual skills in acute stroke is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
ACUTE STROKE PATIENTS: Inclusion Criteria: * acute stroke (\< 21 days) * aged 18-90 years * with a demonstrated stroke (ischemic or hemorrhagic) lesion on brain imaging Exclusion Criteria: * " classical " contre-indication to MRI (non-MR-compatible pacemaker, pregnancy, non-MR-compatible implanted devices, claustrophobia, etc ...) * difficulty in understanding or executing commands * drug/alcohol abuse * severe aphasia / cognitive deficits interfering with study * inability to complete the tasks (i.e. full paralysis of the arm) * multiple strokes / dementia / psychiatric condition HEALTHY INDIVIDUALS: Inclusion Criteria: • 18-90 years Exclusion Criteria: * medical history with a previous stroke / relevant neurological deficit * drug/alcohol abuse * psychiatric condition/ dementia
Where this trial is running
Yvoir, Namur and 1 other locations
- CHU UCL Namur — Yvoir, Namur, Belgium (Recruiting)
- University Hospital CHU Dinant Godinne UCL — Yvoir, Belgium (Recruiting)
Study contacts
- Principal investigator: Yves Vandermeeren, MD, PhD — UCLouvain IONS
- Study coordinator: Yves Vandermeeren, MD, PhD
- Email: yves.vandermeeren@uclouvain.be
- Phone: +32 81 42 33 21
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.