Using an implantable cardiac monitor to detect atrial fibrillation in stroke patients
Yield of Implantable Cardiac Monitoring Device in Patients With Acute Ischemic Stroke.
This study is testing whether an implantable heart monitor can help find atrial fibrillation in stroke patients to see if it can lead to better treatment and prevent future strokes.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 200 (estimated) |
| Ages | 40 Years to 100 Years |
| Sex | All |
| Sponsor | National and Kapodistrian University of Athens Academic / other |
| Locations | 1 site (Athens) |
| Trial ID | NCT05494034 on ClinicalTrials.gov |
What this trial studies
This prospective cohort study aims to investigate the incidence of atrial fibrillation (AF) detected by an implantable cardiac monitoring device in patients who have experienced acute ischemic stroke. Conducted across four tertiary centers in the Athens Metropolitan area, the study will enroll consecutive patients aged 40 years or older diagnosed with acute ischemic stroke or transient ischemic attack (TIA). The research will focus on the association between detected AF, initiation of anticoagulation therapy, and the recurrence of stroke. The study will recruit approximately 200 eligible patients over a four-year period, ensuring informed consent is obtained from participants or their guardians.
Who should consider this trial
Good fit: Ideal candidates for this study are patients aged 40 years or older who have experienced an acute ischemic stroke or TIA and have a HAVOC score of 4 or higher.
Not a fit: Patients with known or newly detected atrial fibrillation at the time of hospitalization will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved detection and management of atrial fibrillation in stroke patients, potentially reducing the risk of stroke recurrence.
How similar studies have performed: Previous studies have shown success in using implantable cardiac monitors for detecting atrial fibrillation, indicating that this approach is promising.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Consecutive acute ischemic stroke or TIA patients aged 40 years or older will be enrolled. * Diagnosis of acute ischemic stroke will be based on clinical and neuroimaging evaluation \[brain computed tomography (CT) scan or magnetic resonance imaging (MRI) scan\]. * Stroke patients of all other etiologies (apart AF) presenting a HAVOC score ≥4 will be included in the study. * Informed consent for participation in the study will be obtained from the patients or guardians of patients. Exclusion Criteria: * Patients with incomplete evaluation will be excluded, as previously described. \[22\] -Patients with known or newly detected AF at hospitalization will also be excluded. * Not providing informed consent.
Where this trial is running
Athens
- Second Department of Neurology, "Attikon" University Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece — Athens, Greece (Recruiting)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.