Predicting and diagnosing spasticity after acute stroke

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is an observational follow-up of patients with acute middle cerebral artery (MCA) strokes who develop hemiparesis, tracking spasticity over the first three months. Investigators will use a new neurophysiological measure (tonic stretch reflex threshold angle, TSRT, and its velocity sensitivity mu) alongside common clinical tests such as the Modified Ashworth Scale to compare timing and severity of spasticity. Detailed brain imaging will be performed to relate lesion location and extent to later spasticity development. The primary goal is to describe the natural history of post-stroke spasticity and determine whether TSRT/mu provides earlier or more objective detection than routine clinical measures.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Acute stroke in Middle Cerebral Artery area resulting in hemiparesis.
* Hemorrhagic or ischemic
* Medically stable
* Able to provide informed consent

Exclusion Criteria:

* Severe cognitive disorders
* Ataxia

Where it's running

• Jewish General Hospital
  Montreal, Quebec, Canada Recruiting

Study contacts

• Principal investigator: Theodore Wein, MD — Montreal Neurological Institute
• Study coordinator: Mindy F. Levin, PT, PhD
• Email: mindy.levin@mcgill.ca
• Phone: 450-688-9550

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.