Evaluating real-world effectiveness of endovascular thrombectomy for stroke in the Asia-Pacific region
Effective Translation of Endovascular Thrombectomy Trials Into Real-world Practice in the Asia-Pacific: a Multicenter, Prospective Registry (ENDURE-APAC)
This study is testing how well a procedure called endovascular thrombectomy works for adults with a certain type of stroke in real-life situations across the Asia-Pacific region.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 350 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Chinese University of Hong Kong Academic / other |
| Drugs / interventions | erenumab |
| Locations | 3 sites (Linyi, Shandong and 2 other locations) |
| Trial ID | NCT05578300 on ClinicalTrials.gov |
What this trial studies
This observational study aims to assess the real-world implementation of endovascular thrombectomy (EVT) for patients with ischemic stroke and suspected large vessel occlusion (LVO) across multiple centers in the Asia-Pacific region. The study will recruit patients over 18 years of age who are undergoing EVT triage and will collect demographic and clinical data to evaluate factors influencing the effectiveness of EVT. By capturing data on patients who could not undergo EVT, the study seeks to identify gaps between clinical trial results and real-world practice. The findings may inform healthcare policies and improve treatment protocols for stroke patients.
Who should consider this trial
Good fit: Ideal candidates for this study are adults over 18 years old with ischemic stroke and suspected large vessel occlusion.
Not a fit: Patients with isolated vertebral artery occlusion not involving the basilar artery will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance the implementation of EVT, leading to better outcomes for stroke patients in real-world settings.
How similar studies have performed: While there have been successful studies on EVT in controlled environments, this study aims to explore its effectiveness in real-world settings, making it a novel approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patient who are over 18 years of age. * Patient with ischemic stroke with suspected large vessel occlusion (LVO), defined as occlusion of the internal carotid artery (ICA), M1 or M2 segment of the middle cerebral artery (MCA), or basilar artery (BA). Exclusion Criteria: * Patient with isolated vertebral artery occlusion not involving the BA.
Where this trial is running
Linyi, Shandong and 2 other locations
- Linyi People's Hospital — Linyi, Shandong, China (Recruiting)
- The Affiliated Hospital of Medical College of Qingdao University — Qingdao, Shandong, China (Recruiting)
- Chinese University of Hong Kong — Hong Kong, Hong Kong (Recruiting)
Study contacts
- Principal investigator: Bonaventure Yiu Ming IP, MB ChB — Chinese University of Hong Kong
- Study coordinator: Bonaventure Yiu Ming IP, MB ChB
- Email: bonaventureip@cuhk.edu.hk
- Phone: 852-28902002
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.