Evaluating real-world effectiveness of endovascular thrombectomy for stroke in the Asia-Pacific region
Official title: Effective Translation of Endovascular Thrombectomy Trials Into Real-world Practice in the Asia-Pacific: a Multicenter, Prospective Registry (ENDURE-APAC)
Run by Chinese University of Hong Kong · NCT05578300 · Data updated 2026-11-12
This study is testing how well a procedure called endovascular thrombectomy works for adults with a certain type of stroke in real-life situations across the Asia-Pacific region.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 350 (estimated) |
| Sponsor | Chinese University of Hong Kong Academic / other |
| Drugs / interventions | erenumab |
| Locations | 3 sites (Linyi, Shandong and 2 other locations) |
| Status | Recruiting |
| Started | October 21, 2022 |
| Main results expected | October 20, 2032 |
| Study ends | December 31, 2032 |
| Registry record updated | March 18, 2026 |
| Trial ID | NCT05578300 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are adults over 18 years old with ischemic stroke and suspected large vessel occlusion.
✕Probably not a fit
Patients with isolated vertebral artery occlusion not involving the basilar artery will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to assess the real-world implementation of endovascular thrombectomy (EVT) for patients with ischemic stroke and suspected large vessel occlusion (LVO) across multiple centers in the Asia-Pacific region. The study will recruit patients over 18 years of age who are undergoing EVT triage and will collect demographic and clinical data to evaluate factors influencing the effectiveness of EVT. By capturing data on patients who could not undergo EVT, the study seeks to identify gaps between clinical trial results and real-world practice. The findings may inform healthcare policies and improve treatment protocols for stroke patients.
Why it matters
Potential benefit: If successful, this study could enhance the implementation of EVT, leading to better outcomes for stroke patients in real-world settings.
How similar studies have gone: While there have been successful studies on EVT in controlled environments, this study aims to explore its effectiveness in real-world settings, making it a novel approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patient who are over 18 years of age. * Patient with ischemic stroke with suspected large vessel occlusion (LVO), defined as occlusion of the internal carotid artery (ICA), M1 or M2 segment of the middle cerebral artery (MCA), or basilar artery (BA). Exclusion Criteria: * Patient with isolated vertebral artery occlusion not involving the BA.
Where it's running
-
Linyi People's Hospital
Linyi, Shandong, China Recruiting -
The Affiliated Hospital of Medical College of Qingdao University
Qingdao, Shandong, China Recruiting -
Chinese University of Hong Kong
Hong Kong, Hong Kong Recruiting
Study contacts
- Principal investigator: Bonaventure Yiu Ming IP, MB ChB — Chinese University of Hong Kong
- Study coordinator: Bonaventure Yiu Ming IP, MB ChB
- Email: bonaventureip@cuhk.edu.hk
- Phone: 852-28902002
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.