Clinical trial Recruiting at 1 site Observational Ages 18 and up

Investigating the immune response in stroke patients

Official title: The Immune Response to Stroke

Run by University of Oslo · NCT05277129 · Data updated 2026-11-12

This study is trying to see if the immune response in stroke patients affects their thinking skills and could lead to better treatments for cognitive decline after a stroke.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment40 (estimated)
SponsorUniversity of Oslo
Academic / other
Locations1 site (Lørenskog)
StatusRecruiting
StartedJune 24, 2021
Main results expectedDecember 31, 2025
Study endsJune 6, 2029
Registry record updatedMarch 14, 2022
Trial IDNCT05277129 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are adults over 18 years who have suffered a stroke within the last 72 hours.

Probably not a fit

Patients with brain hemorrhage, existing immunological diseases, or those unable to provide informed consent will not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to explore the relationship between immune responses and cognitive decline in patients who have experienced a stroke. By analyzing the immune responses of patients within 72 hours post-stroke, the study seeks to determine if an autoimmune response contributes to cognitive impairment. The research focuses on a specific subgroup of stroke patients to better understand the underlying mechanisms of post-stroke dementia. The findings could provide insights into potential therapeutic targets for improving cognitive outcomes after stroke.

Why it matters

Potential benefit: If successful, this study could lead to new strategies for preventing or mitigating cognitive decline in stroke patients.

How similar studies have gone: While the specific hypothesis of autoimmune responses in post-stroke cognitive decline is novel, related studies have explored immune responses in stroke patients with varying degrees of success.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Stroke \< 72 h
* Age \> 18 years

Exclusion Criteria:

* Brain hemorrhage verified by CT or MRI scan
* Previous or present immunological disease or other serious comorbidity
* Ongoing immune respons after infection or vaccination \< 1 month
* Cognitive without ability to understand and/or give an informed consent to participate in the study

Where it's running

  • Akershus University Hospital
    Lørenskog, Norway
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.