Condition

Spinal Cord Injuries clinical trials and research

• 134Clinical trials
• 5NIH research projects
• 1New in 30 days
• 25Countries

Newest Spinal Cord Injuries clinical trials

All recruiting trials (134)

• Transcutaneous spinal cord stimulation with 4-aminopyridine and intensive rehab for chronic spinal cord injury

  This pilot study tests whether combining noninvasive spinal stimulation, dalfampridine, and rigorous rehab is safe and feasible for adults with chronic spinal cord injury and whether it can help improve movement and walking.

  Recruiting TryAbility LLC · Downers Grove, Illinois · NCT07922122

• NG004 for incomplete cervical spinal cord injury

  This trial tests NG004 versus placebo to see if it is safe and helps motor function and daily life in adults with acute incomplete cervical spinal cord injury.

  Recruiting at 7 sites Phase 1 NovaGo Therapeutics AG · Bayreuth and 9 other locations · NCT07840196

• Robot-assisted training for arm and leg movement after stroke or injury

  This study tests whether adding ZEPU-AI robotic training to usual therapy is safe and helps adults with arm or leg movement problems from stroke, spinal cord injury, brain injury, or orthopedic conditions.

  Recruiting Bangladesh Medical University · Dhaka · NCT07749625

• ZEPU-AI3 Lower Limb Feedback Training and Evaluation Robot in Rehab

  This pilot trial tests whether adding the ZEPU-AI3 robotic leg training with real-time feedback to standard rehab helps adults with lower limb motor problems from stroke, spinal cord injury, or similar conditions.

  Recruiting Bangladesh Medical University · Dhaka, Dhaka Division · NCT07705906

• Combined magnetic stimulation and ultrasound for detrusor overactivity in spinal cord injury

  This study tests whether using high-frequency sacral nerve stimulation together with bladder-directed ultrasound can reduce involuntary bladder contractions and improve bladder function in people with spinal cord injury.

  Recruiting Shengjing Hospital · Shenyang · NCT07704268

• Hybrid HIIT-FES cycling program for people with spinal cord injury

  This study tests a hybrid exercise program that combines functional electrical stimulation cycling with voluntary arm work to improve health in adults with spinal cord injury.

  Recruiting William Carey University · Hattiesburg, Mississippi · NCT07648173

• Hands-free self-balancing exoskeleton to help walking after spinal cord injury

  This study will try a hands-free, self-balancing exoskeleton in adults with spinal cord injury to see if it safely helps with standing and walking in daily life.

  Recruiting Wandercraft · Paris · NCT07536386

• Home-based remote ischemic conditioning for people with spinal cord injury

  This project will try remote ischemic conditioning at home to see if it improves heart and metabolic health in adults with spinal cord injury.

  Recruiting Washington University School of Medicine · St Louis, Missouri · NCT07488793

• Rapid early mobilization with seated cycling for people with recent traumatic spinal cord injury (PROMPT-SCI II)

  This study will test whether starting seated cycling within days after a traumatic spinal cord injury is safe and helps improve recovery and reduce complications in adults.

  Recruiting Centre Integre Universitaire de Sante et Services Sociaux du Nord de l'ile de Montreal · Montreal, Quebec · NCT07472985

• TWIICE Rise exoskeleton for assisted walking after spinal cord injury

  This will test two versions of the TWIICE Rise wearable exoskeleton in adults with spinal cord injury to see if they can safely practice walking in clinic, at home, and in the community.

  Recruiting Twiice · Nottwil, Canton of Lucerne · NCT07461259

• Transcutaneous spinal stimulation plus robotic arm training for people with cervical spinal cord injury

  This project will try adding transcutaneous spinal cord stimulation (tSCS) to robotic arm therapy to see if it improves arm and hand function in adults with chronic incomplete cervical spinal cord injuries.

  Recruiting National University Hospital, Singapore · Singapore, Singapore · NCT07432321

• Patient and caregiver perspectives on bladder instillations for urinary symptoms

  This project talks with adults who have neurogenic bladder and their caregivers to see what they prefer and experience with bladder instillations of Lactobacillus, gentamicin, or both.

  Recruiting Medstar Health Research Institute · Washington D.C., District of Columbia · NCT07390591

• Non-invasive spinal stimulation combined with gait training to improve walking after incomplete spinal cord injury

  This tests whether adding non-invasive spinal cord stimulation to gait training helps adults with chronic incomplete spinal cord injury walk better and have less spasticity.

  Recruiting Institut Guttmann · Badalona, Barcelona · NCT07289191

• Testosterone and blood vessel health after spinal cord injury

  This research tests if low testosterone in men with recent motor-complete paraplegia is linked to poorer blood vessel function and higher blood markers of endothelial injury.

  Recruiting Craig Hospital · Englewood, Colorado · NCT07227740

• Blood vessel (endothelial) dysfunction after spinal cord injury

  This research will test whether blood vessels in adults with chronic paraplegia do not widen properly and whether circulating endothelial microvesicles help explain those changes by comparing them to adults without an injury.

  Recruiting Craig Hospital · Englewood, Colorado · NCT07227727

• Spinal Neurorehabilitation for Veterans With SCI

  This study tests non-invasive spinal neuromodulation approaches to see if veterans with long-term spinal cord injury can gain some motor or sensory improvements.

  Recruiting VA Office of Research and Development · Sacramento, California · NCT07222046

• Tracking autonomic blood-pressure changes after spinal cord injury to predict complications

  We will test whether tracking blood pressure and autonomic responses over time in adults with C6–T12 spinal cord injuries can help predict later medical complications.

  Recruiting Mayo Clinic · Rochester, Minnesota · NCT07210437

• How spinal cord stimulation affects blood pressure, immune, and heart function after spinal cord injury

  This research will test whether spinal cord stimulation can change blood pressure control and immune and heart function in adults with spinal cord injury.

  Recruiting Mayo Clinic · Rochester, Minnesota · NCT07210411

• Wearable neuromodulation to help bowel symptoms after spinal cord injury

  This study tests a wearable device that uses transcutaneous neuromodulation to see if it can lessen neurogenic bowel dysfunction in people with spinal cord injury, compared to a sham treatment.

  Recruiting University of Michigan · Ann Arbor, Michigan · NCT07171489

• ARC-IM system to manage symptomatic blood pressure instability after chronic spinal cord injury

  This study will test whether the ARC-IM implant can reduce symptomatic low blood pressure and related symptoms in people with chronic spinal cord injury.

  Recruiting at 13 sites ONWARD Medical, Inc. · Little Rock, Arkansas and 12 other locations · NCT07147296

• Deep brain stimulation of the cuneiform nucleus to improve walking after spinal cord injury

  This trial will try deep brain stimulation of the cuneiform nucleus to improve walking in adults with incomplete spinal cord injuries who cannot walk effectively.

  Recruiting at 2 sites University of Miami · Miami, Florida and 1 other locations · NCT07109804

• Combined threshold pressure respiratory muscle training plus targeted iTBS for improving breathing after spinal cord injury

  This will test whether daily breathing muscle training combined with targeted intermittent theta-burst stimulation (iTBS) helps people with recent spinal cord injuries breathe better.

  Recruiting Shengjing Hospital · Shenyang, Liaoning · NCT07050069

• A new scale to measure body awareness and spatial body maps in adults with spinal cord injury

  This study will test a new questionnaire to measure body awareness and visuospatial body maps in adults with spinal cord injury, including those with and without neuropathic pain.

  Recruiting University of Minnesota · Minneapolis, Minnesota · NCT07029802

• Diet and exercise to manage low blood pressure after meals in spinal cord injury patients

  This study is testing if a special diet and electrical exercises can help people with spinal cord injuries manage low blood pressure after meals.

  Recruiting Ohio State University · Columbus, Ohio · NCT06882460

• Neurorecovery program to improve breathing and arm function after spinal cord injury

  This program will test whether combining short bouts of lowered oxygen (therapeutic intermittent hypoxia) with exercise training can help people with chronic cervical spinal cord injury (tetraplegia) regain breathing and upper‑limb function.

  Recruiting University of Melbourne · Heidelberg, Victoria · NCT06871254

• Home therapy using spinal cord stimulation for patients with spinal cord injuries and multiple system atrophy

  This study is testing a home therapy using a spinal cord stimulation device to see if it helps people with spinal cord injuries or multiple system atrophy manage symptoms like low blood pressure and bowel issues.

  Recruiting University of British Columbia · Vancouver, British Columbia · NCT06838637

• Using Transcranial Magnetic Stimulation to Treat Neuropathic Pain from Spinal Cord Injuries

  This study is testing if a non-invasive brain treatment called rTMS can help reduce neuropathic pain and improve quality of life for people with spinal cord injuries.

  Recruiting Afyonkarahisar Health Sciences University · Afyonkarahisar · NCT06726954

• Effects of a diabetes drug on glucose levels in people with spinal cord injuries

  This study is testing if a diabetes drug called semaglutide can help people with spinal cord injuries better manage their blood sugar levels and improve their overall health.

  Recruiting at 2 sites Phase 4 The University of Texas Health Science Center at San Antonio · San Antonio, Texas and 1 other locations · NCT06706284

• Using electrical stimulation to improve arm function after spinal cord injuries

  This study is testing if a special therapy using electrical stimulation can help people with spinal cord injuries improve their arm function and everyday activities.

  Recruiting University of Miami · Miami, Florida · NCT06672458

• Noninvasive spinal cord stimulation to improve arm function

  This study is testing whether a new type of electrical stimulation can help improve arm function in people with spinal cord injuries or strokes when combined with therapy.

  Recruiting at 2 sites Phase 2/3 University of Alberta · Edmonton, Alberta and 1 other locations · NCT06596369

• Testing EG110A injections for bladder control in spinal cord injury patients

  This study is testing if EG110A injections can help people with spinal cord injuries who have trouble controlling their bladder feel more comfortable and manage their incontinence better.

  Recruiting at 4 sites Phase 1/2 Cyllene Therapeutics · Downey, California and 4 other locations · NCT06596291

• Noninvasive spinal cord stimulation for recovery after spinal cord injury

  This study is testing a new non-invasive treatment to see if it can help improve bladder, bowel, sexual, and heart functions in people who have had a spinal cord injury for a few months.

  Recruiting University of British Columbia · Vancouver, British Columbia · NCT06587841

• Using phage therapy to treat bladder infections in spinal cord injury patients

  This study is testing if a new treatment using viruses to target bacteria can help people with spinal cord injuries who have bladder infections caused by E. coli.

  Recruiting at 2 sites Phase 1 Washington University School of Medicine · St Louis, Missouri and 1 other locations · NCT06559618

• Transcutaneous spinal cord stimulation for recovery after spinal cord injury

  This study is testing if a new type of spinal cord stimulation can help improve heart function and bladder and bowel control in adults recovering from cervical and upper thoracic spinal cord injuries.

  Recruiting University of Washington · Seattle, Washington · NCT06540859

• Using exoskeletons for long-term rehabilitation of lower limb weakness

  This study is testing whether a hands-free exoskeleton can help adults with lower limb weakness from conditions like stroke or spinal cord injury improve their walking, balance, and quality of life over time.

  Recruiting Wandercraft · Paris · NCT06538974

• Low-oxygen sessions and noninvasive spinal stimulation to improve walking after spinal cord injury.

  This study tries short, repeated bouts of mild low oxygen together with noninvasive spinal cord stimulation and walking practice to help adults with chronic spinal cord injury walk better and build leg strength.

  Recruiting at 2 sites Spaulding Rehabilitation Hospital · Jacksonville, Florida and 1 other locations · NCT06521723

• Improving pelvic rehabilitation after spinal cord injury with epidural stimulation

  This study is testing if using a special device to stimulate the spinal cord can help people with spinal cord injuries improve their bladder and bowel function through pelvic rehabilitation.

  Recruiting University College, London · Stanmore · NCT06515223

• Ujjayi yogic breathing to improve heart‑lung synchrony after spinal cord injury

  This trial will try regular Ujjayi yogic breathing with adults 18–60 who have spinal cord injuries to see if it improves breathing patterns, lung function, breathing control, and sleep.

  Recruiting Spaulding Rehabilitation Hospital · Cambridge, Massachusetts · NCT06514950

• Using a brain-computer interface to help people with tetraplegia communicate

  This study is testing a new brain-computer interface to help people with tetraplegia communicate more easily using a tablet.

  Recruiting Massachusetts General Hospital · Boston, Massachusetts · NCT06511934

• Improving arm and hand recovery after spinal cord injury using therapy and stimulation

  This study is testing if combining special therapy with spinal cord stimulation can help people with cervical spinal cord injuries recover better use of their arms and hands.

  Recruiting University Health Network, Toronto · Toronto, Ontario · NCT06472986

• Using rTMS to improve motor function after spinal cord injury

  This study is testing if a new type of brain stimulation can help people with spinal cord injuries improve their movement and reduce pain.

  Recruiting Oslo University Hospital · Oslo, Norway · NCT06464744

• Epidural stimulation to improve motor function in spinal cord injury patients

  This study is testing if epidural stimulation can help people with spinal cord injuries improve their movement and regain some mobility.

  Recruiting Buddhist Tzu Chi General Hospital · Hualien City · NCT06455137

• Managing blood flow after spinal cord injuries

  This study is testing different ways to manage blood flow in people with recent spinal cord injuries to see which method helps them recover better and avoid other health problems.

  Recruiting The University of Texas Health Science Center, Houston · Houston, Texas · NCT06451133

• Investigating pain mechanisms in patients with spinal cord injuries

  This study is trying to understand how spinal cord injuries cause nerve pain by looking at how the body processes pain and responds to it in people with different types of spinal injuries and nerve issues.

  Recruiting University of Zurich · Zurich, Canton of Zurich · NCT06443281

• Investigating how spinal cord injuries affect heart health

  This study looks at how spinal cord injuries affect heart health in adults and tries to find out why they may have a higher risk of heart problems.

  Recruiting Craig Hospital · Englewood, Colorado · NCT06443151

• New treatment for neuropathic pain in spinal cord injury patients

  This study is testing a new oral medication called EC5026 to see if it can safely help people with spinal cord injuries manage their nerve pain.

  Recruiting Phase 1 EicOsis Human Health Inc. · Augusta, Georgia · NCT06438471

• Using AI to analyze data from traumatic cervical spinal cord injuries

  This study is trying to gather and organize detailed information about traumatic cervical spinal cord injuries to help researchers work together better and improve treatments in the future.

  Recruiting Affiliated 2 Hospital of Nantong University · Nantong, Jiangsu · NCT06436716

• Abdominal electrical stimulation to improve bowel function after spinal cord injury.

  We will test whether abdominal electrical stimulation can shorten how long adults with chronic spinal cord injury spend on bowel care.

  Recruiting Craig Hospital · Englewood, Colorado · NCT06345781

• Virtual reality walking game for neuropathic pain relief in spinal cord injury patients

  This study tests if a virtual reality walking game can help adults with spinal cord injuries and ongoing nerve pain feel better.

  Recruiting Texas A&M University · College Station, Texas · NCT06330181

• Combining spinal cord stimulation with arm exercise for heart recovery in spinal cord injury patients

  This study is testing if combining a special spinal cord stimulation with arm exercises can help improve heart health in adults with serious spinal cord injuries.

  Recruiting University of Washington · Seattle, Washington · NCT06313515

• Testing spinal stimulation methods for improving motor function in spinal cord injury patients

  This study is testing different spinal stimulation methods to see if they can help improve movement in people with spinal cord injuries at the C5-C7 level.

  Recruiting University of Manitoba · Winnipeg, Manitoba and 1 other locations · NCT06272279

• High-flow oxygen treatment after spinal cord injury

  This study will test whether giving high-flow oxygen for 10 days helps people with recent neck or upper-back (C4–T4) spinal cord injuries avoid breathing complications.

  Recruiting Cardiff and Vale University Health Board · Cardiff · NCT06244160

• Surgical treatment for spinal cord injuries using nerve grafts

  This study is testing a new surgical method using nerve grafts to see if it can help people with recent spinal cord injuries recover better.

  Recruiting University of Kentucky · Lexington, Kentucky · NCT06243211

• Transcutaneous spinal cord stimulation for children with incomplete spinal cord injury

  This study is testing if a new type of spinal cord stimulation can help children aged 3 to 16 with incomplete spinal cord injuries improve their walking while they receive special training.

  Recruiting Hugo W. Moser Research Institute at Kennedy Krieger, Inc. · Baltimore, Maryland · NCT06242873

• Using epidural stimulation to improve rehabilitation outcomes for cervical spinal cord injuries

  This study is testing if a new treatment using epidural stimulation along with arm exercises can help people with cervical spinal cord injuries improve their arm function.

  Recruiting The Methodist Hospital Research Institute · Houston, Texas · NCT06225245

• Smart rehabilitation for stroke and spinal cord injury patients

  This study tests whether a smart rehabilitation system using a robot can help stroke and spinal cord injury patients improve their movement and daily activities better than a regular home program.

  Recruiting at 2 sites National Cheng-Kung University Hospital · Tainan and 1 other locations · NCT06215625

• Effects of spinal stimulation on muscle control and pain in spinal cord injury patients

  This study is testing how different types of spinal stimulation can help people with spinal cord injuries improve muscle control and reduce pain.

  Recruiting Shepherd Center, Atlanta GA · Atlanta, Georgia · NCT06214208

• Using non-invasive spinal stimulation to improve recovery after spinal cord injury

  This study is testing two non-invasive spinal stimulation methods to see if they can help people with spinal cord injuries recover their ability to stand and move better.

  Recruiting The Methodist Hospital Research Institute · Houston, Texas · NCT06213012

• Autonomic dysreflexia and bladder filling speed in people with spinal cord injury.

  Researchers will test whether different bladder filling speeds during urodynamic testing change how often or how severely autonomic dysreflexia happens in people with chronic spinal cord injury.

  Recruiting Pusan National University Yangsan Hospital · Yangsan, Gyeongsangnam-do · NCT06211491

• Improving walking ability after spinal cord injury with early treadmill therapy

  This study tests if starting treadmill therapy sooner after a spinal cord injury can help people walk better compared to starting later or not at all.

  Recruiting Shirley Ryan AbilityLab · Chicago, Illinois and 1 other locations · NCT06176833

• Using expressive writing to help adults with spinal cord injuries cope with grief

  This study is testing whether a 10-week online writing program can help adults with spinal cord injuries cope with their grief and improve their emotional well-being.

  Recruiting University of Alabama at Birmingham · Birmingham, Alabama · NCT06147258

• Qigong program for managing pain in people with spinal cord injuries

  This study is testing a 12-week online Qigong program to see if it can help adults with spinal cord injuries manage their chronic pain better.

  Recruiting University of Minnesota · Miami, Florida and 2 other locations · NCT06140355

• Optimizing brain and spinal cord stimulation with hand training after spinal cord injury

  The team will test whether pairing brain stimulation with cervical spinal cord stimulation plus hand training improves hand strength and function in adults with chronic cervical spinal cord injury.

  Recruiting Bronx VA Medical Center · The Bronx, New York · NCT06104735

• Using a brain-computer interface to help people with speech difficulties communicate

  This study is testing a brain-computer interface to help people who can't speak due to conditions like ALS communicate by turning their thoughts into speech.

  Recruiting Massachusetts General Hospital · Sacramento, California · NCT06094205

• Preventing central pain after spinal cord injury with Pregabalin

  This study is testing if giving Pregabalin to people with spinal cord injuries early on can help prevent them from developing central pain during their rehabilitation.

  Recruiting Loewenstein Hospital · Raanana · NCT06066918

• Intensive upper limb training for recovery after cervical spinal cord injury

  This study is testing if an 8-week program of intensive arm training can help people with cervical spinal cord injuries recover better and improve their movement.

  Recruiting at 3 sites Hasselt University · Antwerp and 3 other locations · NCT06065384

• Using spinal cord stimulation to improve breathing in patients with spinal cord injuries

  This study is testing if combining spinal cord stimulation with breathing exercises can help improve lung function in people with spinal cord injuries.

  Recruiting University of Louisville · Louisville, Kentucky · NCT06019949

• Breathing treatment for recovery after spinal cord injury

  This study is testing if a new breathing treatment can help people with spinal cord injuries recover their breathing and movement better than a standard treatment.

  Recruiting University of Florida · Jacksonville, Florida · NCT06011876

• Using body illusions and brain stimulation to treat pain in spinal cord injury

  This study is testing if combining body illusions with a type of brain stimulation can help reduce pain and improve sensation in people with spinal cord injuries.

  Recruiting University of Miami · Miami, Florida · NCT06010251

• Education on cardiometabolic risks for spinal cord injury patients

  This study is testing if giving information about heart and metabolic health risks can help people with spinal cord injuries better understand and manage their health after rehab.

  Recruiting University of Miami · Washington D.C., District of Columbia and 2 other locations · NCT06003686

• Using spinal cord stimulation to improve upper limb rehabilitation

  This study is testing if adding a gentle spinal cord stimulation treatment to regular rehab can help people with recent spinal cord injuries improve their arm function and reduce stiffness.

  Recruiting University College, London · London · NCT05991804

• Exploring the Enteric Nervous System in Spinal Cord Injury Patients

  This study is trying to understand how spinal cord injuries affect the gut's nervous system and its ability to function properly, in hopes of finding better treatments for digestive issues in these patients.

  Recruiting Nantes University Hospital · Nantes and 1 other locations · NCT05954845

• Assessing a new therapy to improve mobility in people with chronic spinal cord injury

  This study is testing a new therapy to see if it can help people with chronic spinal cord injuries move better and improve their overall quality of life.

  Recruiting Ecole Polytechnique Fédérale de Lausanne · Lausanne, Canton of Vaud · NCT05942339

• Using Continuous Passive Motion to Prevent Heterotopic Ossification

  This study is trying out a special movement therapy to see if it helps prevent bone growth problems in ICU patients with brain or spinal injuries.

  Recruiting University of Ioannina · Ioannina, Epirus · NCT05906056

• Assessment of a neuroprosthesis device for hand function in spinal cord injury patients

  This study is testing a new device that helps people with cervical spinal cord injuries regain hand movement to see if it can improve their ability to grasp and release objects.

  Recruiting MetroHealth Medical Center · Cleveland, Ohio · NCT05863754

• New ergonomic wheelchair design with multiple gear options

  This study is testing a new wheelchair design with adjustable gears to see if it helps Veterans with spinal cord injuries push more easily and feel less shoulder pain.

  Recruiting VA Office of Research and Development · Minneapolis, Minnesota · NCT05776030

• Neurostimulation to improve breathing after spinal cord injury

  This study is testing if a new type of brain stimulation can help people with cervical spinal cord injuries breathe better.

  Recruiting Shirley Ryan AbilityLab · Chicago, Illinois · NCT05756894

• Telefitting spinal cord stimulation for chronic pain management

  This study is testing different types of spinal cord stimulation to see which one helps people with chronic back pain feel better.

  Recruiting University of Minnesota · Minneapolis, Minnesota · NCT05741788

• Transcutaneous spinal stimulation to improve blood pressure after a recent spinal cord injury

  We will try a noninvasive spinal stimulation to see if it raises and steadies blood pressure in people 7–30 days after a thoracic spinal cord injury who have low blood pressure or dizziness when sitting up.

  Recruiting Kessler Foundation · West Orange, New Jersey · NCT05731986

• Transcutaneous spinal stimulation to stabilize blood pressure after spinal cord injury

  This will test whether noninvasive transcutaneous spinal cord stimulation can raise and stabilize blood pressure in people with chronic high-level spinal cord injuries who experience orthostatic hypotension.

  Recruiting Kessler Foundation · West Orange, New Jersey · NCT05725499

• Using a neural interface to help people with tetraplegia control devices with their thoughts

  This study is testing a new brain interface that helps people with tetraplegia, especially those with ALS, control devices like computers just by thinking about it.

  Recruiting at 2 sites Massachusetts General Hospital · Stanford, California and 1 other locations · NCT05724173

• Examining changes in the central nervous system after spinal cord injury

  This study is trying to see how spinal cord injuries affect the brain and nervous system in both new and long-term patients to help improve treatments for recovery.

  Recruiting University of Zurich · Zurich · NCT05681936

• Examining the gut microbiome's effects on metabolic and bowel function after spinal cord injury

  This study is trying to see how the gut bacteria of people with a recent spinal cord injury affects their metabolism and bowel function over the first year after the injury.

  Recruiting University of Alabama at Birmingham · Birmingham, Alabama · NCT05670288

• Using Transcranial Magnetic Stimulation to Treat Neuropathic Pain in Spinal Cord Injury Patients

  This study is testing whether a type of brain stimulation called rTMS can help reduce neuropathic pain in people with spinal cord injuries.

  Recruiting Afyonkarahisar Health Sciences University · Afyonkarahisar · NCT05645003

• Evaluating the Nomad powered KAFO for improving mobility in individuals with lower-extremity impairments

  This study is testing if a new powered brace can help people with leg injuries move better and feel more balanced compared to their regular braces.

  Recruiting Shirley Ryan AbilityLab · Chicago, Illinois · NCT05644522

• Using a robotic exoskeleton for upper limb rehabilitation in spinal cord injury patients

  This study is testing a robotic device to help people with spinal cord injuries improve their arm movement and independence during rehabilitation.

  Recruiting at 2 sites University of Liverpool · London and 1 other locations · NCT05615766

• Combining low oxygen therapy and spinal stimulation to improve walking after spinal cord injury

  This study is testing if combining low oxygen therapy with spinal stimulation and walking training can help people with chronic spinal cord injuries walk better.

  Recruiting at 2 sites Spaulding Rehabilitation Hospital · Chicago, Illinois and 1 other locations · NCT05563103

• A device to assist hand function for people with spinal cord injuries

  This study is testing a new device called MyHand-SCI to see if it can help people with C6-C7 spinal cord injuries improve their hand function and daily activities.

  Recruiting Columbia University · New York, New York · NCT05553457

• Using rTMS to Treat Depression in Veterans with Spinal Cord Injuries

  This study is testing a new way to use brain stimulation to help veterans with spinal cord injuries who are struggling with depression.

  Recruiting VA Office of Research and Development · Charleston, South Carolina · NCT05553353

• Training leg reflexes to reduce neuropathic pain after spinal cord injury

  This study is testing whether training leg reflexes can help reduce neuropathic pain in people with spinal cord injuries.

  Recruiting Medical University of South Carolina · Charleston, South Carolina · NCT05492188

• Comparing Apixaban and Enoxaparin for preventing blood clots after spinal cord injury

  This study is testing if a new blood thinner called Apixaban works better than the usual treatment, Enoxaparin, to prevent blood clots in people recovering from spinal cord injuries.

  Recruiting Loewenstein Hospital · Raanana · NCT05484557

• Impact of Sleep Efficiency on Motor Impairment in Spinal Cord Injury

  This study is testing if starting CPAP therapy early or later helps people with spinal cord injuries and sleep problems improve their movement abilities.

  Recruiting University Health Network, Toronto · Toronto, Ontario · NCT05473689

• Exploring spinal cord stimulation and training for spinal cord injuries

  This study is testing if spinal cord stimulation can help improve movement and recovery in people with spinal cord injuries by looking at how it affects their nervous system.

  Recruiting Washington University School of Medicine · St Louis, Missouri · NCT05472584

• Breathing high oxygen levels to improve function after spinal cord injury

  This study is testing if breathing in high levels of oxygen for a short time can help improve movement and feeling in people with serious spinal cord injuries.

  Recruiting Early Phase 1 University of Alberta · Edmonton, Alberta · NCT05467215

• Effects of Physical Therapy on Wound Healing in Spinal Cord Injury Patients

  This study is testing whether different types of physical therapy can help improve wound healing in people with spinal cord injuries.

  Recruiting Wake Forest University Health Sciences · Charlotte, North Carolina · NCT05458947

• Using smartphone technology and e-coaching to improve exercise adherence for spinal cord injury patients

  This study is testing a smartphone app and e-coaching program to see if it can help people with spinal cord injuries stick to their exercise routines and improve their health.

  Recruiting Shirley Ryan AbilityLab · Chicago, Illinois · NCT05424172

• Using mild intermittent hypoxia to prevent autonomic dysfunction in spinal cord injury patients

  This study is testing if mild intermittent hypoxia can help people with spinal cord injuries improve their blood pressure control and overall health by preventing autonomic dysfunction.

  Recruiting VA Office of Research and Development · Detroit, Michigan · NCT05351827

• New rehabilitation approach for walking recovery after spinal cord injury

  This study is testing a new rehab program that combines downhill treadmill training and electrical stimulation to see if it helps people with spinal cord injuries walk better.

  Recruiting at 2 sites Ohio State University · Columbus, Ohio and 1 other locations · NCT05337982

• Training wrist muscle responses in people with incomplete spinal cord injuries

  This study is testing whether targeted training can improve wrist movement in people with incomplete spinal cord injuries by strengthening the connection between their brain and muscles.

  Recruiting Medical University of South Carolina · Charleston, South Carolina · NCT05321017

• Improving physical activity for individuals with spinal cord injury using smartphones

  This study is testing if using a smartphone app that gives personalized feedback can help people with spinal cord injuries be more active compared to a regular online program.

  Recruiting Phase 2 Temple University · Philadelphia, Pennsylvania · NCT05317832

• Non-invasive spinal stimulation to improve arm function after spinal cord injury

  This study is testing if a new type of electrical stimulation can help improve arm movement and reduce stiffness in people with spinal cord injuries.

  Recruiting University of Washington · Seattle, Washington · NCT05267951

• Evaluating blood biomarkers for spinal cord injury recovery

  This study is testing whether certain blood markers can help doctors understand the severity of spinal cord injuries and predict how well patients will recover.

  Recruiting University of British Columbia · Vancouver, British Columbia · NCT05244408

• Comparing Lactobacillus Rhamnosus GG with saline bladder wash for preventing UTIs in spinal cord injury patients

  This study is testing if a special probiotic combined with a saline bladder wash can help prevent urinary tract infections in people with spinal cord injuries.

  Recruiting Phase 2 Medstar Health Research Institute · Washington D.C., District of Columbia · NCT05230511

• Using a powered exoskeleton with electrical stimulation to help patients with spinal cord injuries walk better

  This study is testing if using a powered exoskeleton along with electrical stimulation can help people with spinal cord injuries walk better and improve their overall health.

  Recruiting Swiss Paraplegic Research, Nottwil · Nottwil, Canton of Lucerne · NCT05187650

• Using brain-computer interfaces to control assistive devices for motor recovery

  This study tests whether using brain-computer interfaces can help people with motor disorders control assistive devices better and improve their movement skills.

  Recruiting University of Texas at Austin · Austin, Texas · NCT05183152

• Improving breathing in spinal cord injury patients using stimulation and training

  This study is testing if combining spinal cord stimulation with breathing exercises can help improve breathing in patients with spinal cord injuries.

  Recruiting University of Louisville · Louisville, Kentucky · NCT05178056

• Using stem cells from umbilical cords to treat spinal cord injuries

  This study is testing if stem cells from umbilical cords can safely help people with spinal cord injuries recover and improve over time.

  Recruiting at 2 sites Phase 1 The Foundation for Orthopaedics and Regenerative Medicine · Naples, Florida and 1 other locations · NCT05152290

• Using electrical stimulation to improve blood flow and trunk control in spinal cord injury patients

  This study is testing a new electrical stimulation therapy to see if it can help people with spinal cord injuries improve their blood flow and trunk control.

  Recruiting Ecole Polytechnique Fédérale de Lausanne · Lausanne, Canton of Vaud · NCT05111093

• Training system to improve spinal reflexes in individuals with spinal cord injuries

  This study is testing a new training system to see if it can help people with spinal cord injuries reduce leg stiffness and improve their movement.

  Recruiting Medical University of South Carolina · Charleston, South Carolina and 1 other locations · NCT05094362

• Comparing two types of stem cell injections for spinal cord injury treatment

  This study is testing which type of stem cell injection works better for helping people with spinal cord injuries recover.

  Recruiting at 2 sites Phase 1 The Foundation for Orthopaedics and Regenerative Medicine · Naples, Florida and 1 other locations · NCT05018793

• Using virtual reality walking games to help with neuropathic pain in spinal cord injury patients

  This study is testing whether playing virtual reality walking games can help adults with spinal cord injuries and ongoing nerve pain feel better.

  Recruiting at 2 sites Texas A&M University · Birmingham, Alabama and 2 other locations · NCT05005026

• Closed-loop spinal cord stimulation for improving walking in spinal cord injury patients

  This study is testing if a new type of spinal cord stimulation can help people with spinal cord injuries walk better during their rehab.

  Recruiting Phase 1 Tsinghua University · Beijing, Beijing Municipality · NCT04969042

• Understanding how the reticulospinal system controls movement

  This study is testing how a part of the nervous system helps people with spinal cord injuries move by using surprising sounds to see how quickly they can react and move.

  Recruiting University of Zurich · Zurich · NCT04967274

• Surgical procedure to improve outcomes after spinal cord injury

  This study is testing if a new surgery that adds a patch to relieve pressure on the spinal cord can help adults with severe spinal cord injuries get stronger and improve their quality of life compared to standard surgery alone.

  Recruiting at 29 sites St George's, University of London · Innsbruck and 33 other locations · NCT04936620

• Training to improve hand and arm function in people with spinal cord injuries

  This study is testing whether a new training program that combines physical exercises with electrical stimulation can help people with spinal cord injuries use their hands and arms better and improve their daily lives.

  Recruiting Kessler Foundation · West Orange, New Jersey · NCT04921592

• Evaluation of new MRI techniques for spinal cord lesions

  This study is testing a new MRI technique to see if it can better detect inflammation in the spinal cord for people with spinal cord lesions.

  Recruiting Fondation Ophtalmologique Adolphe de Rothschild · Paris · NCT04906928

• Improving breathing in patients with cervical spinal cord injuries using neuromodulation

  This study is testing if a special device can help people with cervical spinal cord injuries breathe better and reduce their reliance on ventilators.

  Recruiting at 2 sites University of California, Los Angeles · Los Angeles, California and 1 other locations · NCT04883463

• Improving movement and bladder function in people with spinal cord injuries

  This study is testing if a new treatment using epidural stimulation can help people with spinal cord injuries improve their ability to stand, walk, and manage their bladder.

  Recruiting Kessler Foundation · West Orange, New Jersey · NCT04879862

• Epidural stimulation and resistance training for spinal cord injury recovery

  This study is testing whether combining epidural stimulation with assisted walking and strength training can help people with spinal cord injuries improve their movement and muscle strength.

  Recruiting Phase 2/3 United States Department of Defense · Richmond, Virginia · NCT04782947

• EESS and automated rehabilitation for incomplete spinal cord injuries

  A therapy combining epidural electrical stimulation of the lower spine with automated rehabilitation is being tested to see if it helps adults with incomplete spinal cord injuries walk better or regain function.

  Recruiting at 2 sites Hopital Foch · Garches and 1 other locations · NCT04496609

• Combining testosterone therapy with walking training to improve health after spinal cord injury

  This study is testing if combining testosterone therapy with walking training can help men with spinal cord injuries who have low testosterone and trouble walking improve their health and mobility.

  Recruiting at 2 sites Phase 2 North Florida Foundation for Research and Education · Gainesville, Florida and 1 other locations · NCT04460872

• Treatment for depression in individuals with spinal cord injuries

  This study is testing if a new treatment called rTMS can help people with spinal cord injuries who are also dealing with depression feel better.

  Recruiting Medical University of South Carolina · Charleston, South Carolina · NCT04263285

• New technology for deep brain stimulation to treat chronic pain

  This study is testing a new type of brain stimulation to see if it can help people with chronic pain that doesn't respond to regular treatments.

  Recruiting University of California, San Francisco · San Francisco, California · NCT04144972

• Improving seated balance for wheelchair users with spinal cord injuries using an exoskeleton

  This study is testing if using an exoskeleton while walking can help wheelchair users with spinal cord injuries improve their balance while seated.

  Recruiting James J. Peters Veterans Affairs Medical Center · The Bronx, New York · NCT04047992

• Improving sleep-related issues in spinal cord injury patients with CPAP therapy

  This study is testing if using CPAP therapy at night can help improve sleep problems and overall well-being in adults with spinal cord injuries who have breathing issues during sleep.

  Recruiting University Health Network, Toronto · Toronto, Ontario · NCT04007380

• Understanding CNS Changes After Spinal Cord Injury

  This study looks at how the brain and nervous system change after a spinal cord injury to see if these changes can help predict recovery and understand symptoms better.

  Recruiting University of Zurich · Zurich · NCT03772548

• Restoring hand and wrist function in people with tetraplegia using a neural device

  This study is testing a new device to see if it can help people with tetraplegia regain movement and feeling in their hands and wrists.

  Recruiting Northwell Health · Manhasset, New York · NCT03680872

• Improving movement in people with spinal cord injuries using electrical stimulation and exercise

  This study is testing whether a mix of electrical stimulation and physical therapy can help people with spinal cord injuries move better and improve their daily lives.

  Recruiting University of Washington · Seattle, Washington · NCT03509558

• Epidural stimulation to improve movement and autonomic function after spinal cord injury

  This study is testing if epidural stimulation can help people with complete spinal cord injuries improve their movement and overall health.

  Recruiting University of Minnesota · Minneapolis, Minnesota · NCT03026816

• Mobile health system for managing chronic health conditions

  This study tests a mobile health system that helps people with chronic conditions like spinal cord injuries and cerebral palsy manage their health better by using apps for reminders and tracking symptoms.

  Recruiting University of Pittsburgh · Pittsburgh, Pennsylvania · NCT02592291

• Neuroprosthetic system to restore motor function in spinal cord injury

  This study is testing a new implanted device to see if it can help people with cervical spinal cord injuries regain hand function and improve their ability to move and be independent.

  Recruiting MetroHealth Medical Center · Cleveland, Ohio · NCT02329652

• Breathing low oxygen to improve movement after spinal injury

  This study is testing if breathing low oxygen for short periods can help people with chronic spinal cord injuries improve their movement and walking ability when combined with exercise.

  Recruiting Spaulding Rehabilitation Hospital · Cambridge, Massachusetts · NCT02323945

• Feasibility of a brain-computer interface for people with tetraplegia

  This study is testing a new brain-computer interface that helps people with tetraplegia control a computer and other devices just by thinking, to see if it’s safe and effective.

  Recruiting at 6 sites Massachusetts General Hospital · Sacramento, California and 5 other locations · NCT00912041

• Evaluation of a neuroprosthesis for improving mobility in paralyzed individuals

  This study is testing a new device that helps people with paralysis improve their movement and balance through a special electrical stimulation system implanted in their muscles.

  Recruiting at 2 sites Case Western Reserve University · Cleveland, Ohio and 1 other locations · NCT00623389

NIH-funded research (5)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Delivering targeted, painless nerve growth factor to the spinal cord to help people with spinal cord injuries

  A researcher team is testing a new way to safely deliver nerve growth factor directly to the spinal cord to help people recover after a traumatic injury.

  NIH research Tulane University of Louisiana · New Orleans, United States · NIH-11412690

• Intraoral wearable with a tongue-based interface to control devices for people with cervical spinal cord injuries or ALS

  A small mouth-held device lets a user move a cursor and operate devices with their tongue, helping people with quadriplegia communicate and interact more easily.

  NIH research Augmental Technologies INC. · San Francisco, United States · NIH-11403178

• CSF 5-HIAA as a biomarker for secondary injury after spinal cord trauma

  A study to see if CSF 5-HIAA levels can signal ongoing brain/spinal cord damage after a traumatic spinal cord injury, with potential to guide early treatment.

  NIH research University of Florida · Gainesville, United States · NIH-11393127

• Brief low-oxygen sessions to prevent blood pressure problems after high spinal cord injury

  This project tries to prevent dangerous blood pressure swings in people with high spinal cord injuries by giving short, controlled bouts of mild low oxygen.

  NIH research John D Dingell VA Medical Center · Detroit, United States · NIH-11222655

• Using mild intermittent hypoxia to help manage blood pressure issues in people with spinal cord injuries

  This study is looking at how short periods of low oxygen might help people with spinal cord injuries above the 6th thoracic vertebrae manage their blood pressure and improve their overall health, especially when it comes to sleep problems.

  NIH research John D Dingell VA Medical Center · Detroit, United States · NIH-10938034

Related topics

Quick answers

How many Spinal Cord Injuries clinical trials are recruiting right now?

134, as of November 12, 2026. 1 of them was first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 25 countries. The most sites are in United States (86 trials), Canada (12 trials), Switzerland (9 trials), United Kingdom (5 trials), China (5 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 1: 6, Phase 2: 3, Phase 2/3: 2, Phase 4: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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