Using exoskeletons for long-term rehabilitation of lower limb weakness

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical investigation focuses on the use of a hands-free exoskeleton, the Atalante X, to provide long-term rehabilitation for adults suffering from lower limb weaknesses due to various conditions such as stroke or spinal cord injury. The study aims to assess the effectiveness of this technology in improving gait, balance, and overall quality of life over an extended period. Participants will engage in a structured rehabilitation program that emphasizes sustained motivation and management of their conditions. The study is designed to gather long-term follow-up data to address the current gaps in rehabilitation frameworks.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patient suffering from lower limb weaknesses and / or deficiencies regardless of the cause
* Adult patient ≥18 years old
* Patient able to read and write in French and who have signed an informed consent form
* Patient affiliated to a social security system.

Exclusion Criteria:

* Individual with severe spasticity of adductor muscles, hamstring, quadriceps and triceps surae. Severe spasticity is defined by a score of 4 on the modified Ashworth scale
* Pregnant woman
* Individual with history of osteoporotic fracture and / or pathology or treatment causing secondary osteoporosis
* Pressure Ulcer of Grade I or higher according to the NPUAP International Pressure Ulcer Classification System- EPUAP, in areas of contact with the Atalante X system
* Severe aphasia limiting ability to express needs or to fulfil questionnaires, at the discretion of the physician.
* Patient with a cardiac or respiratory contraindication to physical exertion, at discretion of the physician
* Patient unable to deliver his/her consent
* Patient under legal protection
* Patient participating at the same time in another study
* Patients with morphological contraindications to the use of the Atalante X exoskeleton (as per user's manual) with exceptions as follows: knee flessum of 20° authorized if sensibility is present; equinus of the ankle of 20° allowed regardless of presence or absence of sensibility, hip flessum of 20° allowed regardless of presence or absence of sensibility.

Where it's running

• Wandercraft
  Paris, France Recruiting

Study contacts

• Principal investigator: Rebecca Sauvagnac, MD — Wandercraft
• Study coordinator: Rebecca Sauvagnac, MD
• Email: rebecca.sauvagnac@wandercraft.health
• Phone: +33 (0)1 79 35 31 09

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• TWIICE Rise exoskeleton for assisted walking after spinal cord injury

  This will test two versions of the TWIICE Rise wearable exoskeleton in adults with spinal cord injury to see if they can safely practice walking in clinic, at home, and in the community.

  Recruiting Twiice · Nottwil, Canton of Lucerne · NCT07461259

• Non-invasive spinal stimulation combined with gait training to improve walking after incomplete spinal cord injury

  This tests whether adding non-invasive spinal cord stimulation to gait training helps adults with chronic incomplete spinal cord injury walk better and have less spasticity.

  Recruiting Institut Guttmann · Badalona, Barcelona · NCT07289191

• Evaluating the Nomad powered KAFO for improving mobility in individuals with lower-extremity impairments

  This study is testing if a new powered brace can help people with leg injuries move better and feel more balanced compared to their regular braces.

  Recruiting Shirley Ryan AbilityLab · Chicago, Illinois · NCT05644522

• Using a powered exoskeleton with electrical stimulation to help patients with spinal cord injuries walk better

  This study is testing if using a powered exoskeleton along with electrical stimulation can help people with spinal cord injuries walk better and improve their overall health.

  Recruiting Swiss Paraplegic Research, Nottwil · Nottwil, Canton of Lucerne · NCT05187650

• Using brain-computer interfaces to control assistive devices for motor recovery

  This study tests whether using brain-computer interfaces can help people with motor disorders control assistive devices better and improve their movement skills.

  Recruiting University of Texas at Austin · Austin, Texas · NCT05183152

• Combining testosterone therapy with walking training to improve health after spinal cord injury

  This study is testing if combining testosterone therapy with walking training can help men with spinal cord injuries who have low testosterone and trouble walking improve their health and mobility.

  Recruiting at 2 sites Phase 2 North Florida Foundation for Research and Education · Gainesville, Florida and 1 other locations · NCT04460872

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.