Evaluating the Nomad powered KAFO for improving mobility in individuals with lower-extremity impairments

Power Forward Study: A Cross-Sector, Multisite Clinical Trial of a Powered Knee-Ankle-Foot Orthosis

Not applicable Interventional Shirley Ryan AbilityLab · NCT05644522

This study is testing if a new powered brace can help people with leg injuries move better and feel more balanced compared to their regular braces.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment36 (estimated)
Ages18 Years to 89 Years
SexAll
SponsorShirley Ryan AbilityLab Academic / other
Locations1 site (Chicago, Illinois)
Trial IDNCT05644522 on ClinicalTrials.gov

What this trial studies

This clinical trial aims to assess the effectiveness of the Nomad powered knee-ankle-foot orthosis (P-KAFO) in enhancing mobility, balance, and quality of life for individuals who have experienced musculoskeletal or neurological injuries. Participants will use both their own brace and the Nomad device over a three-month period, with their activities monitored through sensors. The study will compare the outcomes of using the Nomad P-KAFO against the participants' existing braces to determine improvements in mobility and reduction in falls.

Who should consider this trial

Good fit: Ideal candidates include individuals with neurological or neuromuscular diseases who regularly use a KAFO or similar device.

Not a fit: Patients with severe joint contractures, spasticity, or those unable to stabilize their trunk may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could significantly enhance mobility and quality of life for patients with lower-extremity impairments.

How similar studies have performed: While the specific Nomad P-KAFO approach may be novel, similar studies evaluating powered orthoses have shown promising results in improving mobility.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Regular and compliant use of a unilateral or bilateral KAFO or SCO or other passive KAFOs for impairment due to neurological or neuromuscular disease, orthopedic disease, or trauma
* Cognitive ability to understand and follow the study protocol; willingness to provide informed consent
* Willing to wear and charge an activity monitor for three-months home trials.

Exclusion Criteria:

* Flexion contracture in the knee and/or hip joint in excess of 15 degrees
* Non-correctable knee varus/valgus in excess of 15 degrees
* Severe spasticity
* Inability to stabilize the trunk with or without assistive devices (crutches, canes, etc.)

Where this trial is running

Chicago, Illinois

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Cerebrovascular AccidentPost-polio SyndromeSpinal Cord InjuriesMultiple SclerosisMuscular DystrophyParalysis
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.