Spinal Neurorehabilitation for Veterans With SCI

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This project examines how non-invasive spinal neuromodulation and related neurophysiological assessments might help improve function for individuals with chronic spinal cord injuries. Researchers will engage stakeholders to identify priorities and barriers to participation, collect survey data from veterans and SCI physicians, and perform qualitative feedback before and after preliminary neuromodulation experiments. The study uses neurophysiological and anatomical testing, including transcutaneous spinal stimulation, to explore residual connectivity and potential functional gains. Results will inform trial design and eligible patient profiles for future, more targeted interventions. This work represents an initial step toward optimizing neuromodulation-based treatment strategies for veterans with SCI.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* All participants must be able to independently read and understand study information materials necessary to ensure informed consent
* All participants must have a chronic spinal cord injury occurring \>1 year prior to study enrollment
* Ability to follow simple commands in English

Exclusion Criteria:

* Contraindications to the use of external magnetic or electrical stimulation (e.g., epilepsy, intracranial metal, implanted electrosensitive device, etc.)
* Significant neurological comorbidities that may affect neurophysiological recordings
* Functional disability prior to spinal cord injury
* Visual or auditory disorders limiting ability to participate in study procedures
* Pregnancy
* Primary psychiatric disorders or dissociative mental symptoms that impair informed consent
* Significant chronic pain that may preclude an magnetic resonance imaging (MRI) scan or performing neurorehabilitation exercises
* Frequent and significant spasticity that may preclude an MRI scan or neurorehabilitation exercises

Where it's running

• VA Northern California Health Care System, Mather, CA
  Sacramento, California, United States Recruiting

Study contacts

• Principal investigator: Jonathan S Calvert, PhD MD — VA Northern California Health Care System, Mather, CA
• Study coordinator: Jonathan S Calvert, PhD MD
• Email: Jonathan.Calvert2@va.gov
• Phone: (916) 843-7512

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.