Evaluation of new MRI techniques for spinal cord lesions
Evaluation of the Performance of a 3D FGAPSIR Sequence by MRI in the Detection and Characterization of Spinal Cord Injuries in Patients With Multiple Sclerosis
This study is testing a new MRI technique to see if it can better detect inflammation in the spinal cord for people with spinal cord lesions.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 200 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Fondation Ophtalmologique Adolphe de Rothschild Research network |
| Locations | 1 site (Paris) |
| Trial ID | NCT04906928 on ClinicalTrials.gov |
What this trial studies
This study aims to optimize the imaging of inflammatory spinal cord lesions using advanced MRI sequences, including a novel 3D FGAPSIR technique. Participants will undergo standard imaging protocols alongside this new sequence to assess its effectiveness. The study involves verifying inclusion criteria, obtaining consent, and performing MRI scans that include both traditional and new imaging methods. The total examination time will be slightly extended to incorporate the additional sequence.
Who should consider this trial
Good fit: Ideal candidates are adults over 18 who require a medullary exploration via 3T MRI for inflammatory spinal cord assessment.
Not a fit: Patients with legal protection measures, pregnant or breastfeeding women, or those with contraindications to MRI may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance the accuracy of diagnosing and monitoring spinal cord injuries.
How similar studies have performed: While this approach is innovative, similar studies have shown promise in improving MRI techniques for spinal conditions.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patient over 18 years old * To benefit from a medullary exploration planned by 3T MRI as part of a first evaluation or a reassessment of inflammatory involvement of the nevrax * Express consent to participate in the study * Affiliate or beneficiary of a social security scheme Exclusion Criteria: * Patient benefiting from a legal protection measure * Pregnant, parturient or breastfeeding woman * Absolute or relative contraindication to MRI
Where this trial is running
Paris
- Fondation Ophtalmologique Adolphe de Rothschild (FOR) — Paris, France (Recruiting)
Study contacts
- Study coordinator: amélie YAVCHITZ
- Email: ayavchitz@for.paris
- Phone: 0148036454
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.