Combined magnetic stimulation and ultrasound for detrusor overactivity in spinal cord injury

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The trial assesses whether combining two therapies—high-frequency sacral nerve root magnetic stimulation and bladder-directed ultrasound—provides added benefit over magnetic stimulation alone for detrusor overactivity in SCI. Participants are randomly assigned to receive magnetic stimulation, bladder ultrasound, or both, once daily for three weeks (seven sessions per week). Before and after treatment, urodynamic testing and bladder/urinary tract ultrasound assess safety and bladder health, along with voiding diaries and validated quality-of-life questionnaires. The study is conducted at the Rehabilitation Center of Shengjing Hospital in Shenyang, China, sponsored by Shengjing Hospital.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Diagnosis of spinal cord injury (SCI) above the sacral level according to the International Standards for Neurological Classification of Spinal Cord Injury (revised 2011), confirmed by CT or MRI;
2. Detrusor overactivity confirmed by urodynamic study;
3. No severe urinary system diseases such as tumors, stones, infection, or organic urinary tract obstruction;
4. No severe hepatic/renal insufficiency, pulmonary, or cardiovascular diseases;
5. Aged 18-80 years;
6. Able to understand and comply with the required examinations, rehabilitation assessments, and treatment, and provide written informed consent.

Exclusion Criteria:

1. Unstable vital signs or critically ill condition;
2. Severe autonomic dysreflexia;
3. Presence of metallic implants within 10 cm of the magnetic stimulation treatment area;
4. Any other diseases or conditions that may interfere with the study outcomes.

Where it's running

• Rehabilitation Center of Shengjing Hospital, China Medical University, shenyang, Liaoning 110000
  Shenyang, China Recruiting

Study contacts

• Principal investigator: Xue Jiang — Rehabilitation Center of Shengjing Hospital, China Medical University
• Study coordinator: Xue Jiang
• Email: jiangxueruby@163.com
• Phone: +86 18940254064

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.