Using Transcranial Magnetic Stimulation to Treat Neuropathic Pain in Spinal Cord Injury Patients

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the effects of high-frequency Repetitive Transcranial Magnetic Stimulation (rTMS) therapy on neuropathic pain in patients with spinal cord injuries. The therapy targets the dorsolateral prefrontal cortex (DLPFC), an area that has been less studied compared to the primary motor cortex. Participants will receive either active rTMS or a sham treatment to assess the efficacy of this non-invasive brain stimulation technique in alleviating pain. The study aims to provide insights into the potential benefits of rTMS as an adjunct to existing pain management strategies for spinal cord injury patients.

Why it matters

Who can join: the full rules

Inclusion Criteria:

Between the ages of 20-70, who applied to the AFSU Physical Medicine and Rehabilitation inpatient service with the diagnosis of spinal cord injury and

* Having spinal cord injury with neurophatic pain at least six months ago,
* Able to follow two-stage verbal commands,
* Agreeing to participate in the study voluntarily and regularly,
* Patients who are medically stable (no previous myocardial infarction, no musculoskeletal problems) will be included in our study.

Exclusion Criteria:

Having an important comorbid disease such as severe heart disease (aortic stenosis, angina, hypertrophic cardiomyopathy, arrhythmia, pacemaker) and uncontrolled hypertension,

* Epilepsy,
* History of antiepileptic drug use,
* Intracranial metal object,
* Presence of in-ear implant,
* Cognitive dysfunction,
* Lower extremity peripheral nerve injury,
* With malignancy and active infection,
* Infection on the skin in the application area,
* Having an open wound,
* Having inflammatory disease,
* Orthopedic injuries that can limit maximum effort contractions,
* Having a brain lesion or a history of drug use that will affect the seizure threshold,
* Patients with increased intracranial pressure or uncontrolled migraine will not be included.

Where it's running

• Afyonkarahisar
  Afyonkarahisar, Turkey (Türkiye) Recruiting

Study contacts

• Principal investigator: Nuran EYVAZ, MD — Afyonkarahisar Health Sciences University
• Study coordinator: Nuran EYVAZ, MD
• Email: n_eyvaz@hotmail.com
• Phone: +905334262442

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Using Transcranial Magnetic Stimulation to Treat Neuropathic Pain from Spinal Cord Injuries

  This study is testing if a non-invasive brain treatment called rTMS can help reduce neuropathic pain and improve quality of life for people with spinal cord injuries.

  Recruiting Afyonkarahisar Health Sciences University · Afyonkarahisar · NCT06726954

• New treatment for neuropathic pain in spinal cord injury patients

  This study is testing a new oral medication called EC5026 to see if it can safely help people with spinal cord injuries manage their nerve pain.

  Recruiting Phase 1 EicOsis Human Health Inc. · Augusta, Georgia · NCT06438471

• Virtual reality walking game for neuropathic pain relief in spinal cord injury patients

  This study tests if a virtual reality walking game can help adults with spinal cord injuries and ongoing nerve pain feel better.

  Recruiting Texas A&M University · College Station, Texas · NCT06330181

• Using body illusions and brain stimulation to treat pain in spinal cord injury

  This study is testing if combining body illusions with a type of brain stimulation can help reduce pain and improve sensation in people with spinal cord injuries.

  Recruiting University of Miami · Miami, Florida · NCT06010251

• Training leg reflexes to reduce neuropathic pain after spinal cord injury

  This study is testing whether training leg reflexes can help reduce neuropathic pain in people with spinal cord injuries.

  Recruiting Medical University of South Carolina · Charleston, South Carolina · NCT05492188

• Using virtual reality walking games to help with neuropathic pain in spinal cord injury patients

  This study is testing whether playing virtual reality walking games can help adults with spinal cord injuries and ongoing nerve pain feel better.

  Recruiting at 2 sites Texas A&M University · Birmingham, Alabama and 2 other locations · NCT05005026

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.