Preventing central pain after spinal cord injury with Pregabalin

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial aims to evaluate the effectiveness of Pregabalin in preventing the development of central pain in patients who have experienced a spinal cord injury (SCI) and are undergoing rehabilitation. Patients who arrive at the rehabilitation center within three months of their injury will be divided into two groups: one receiving Pregabalin and the other receiving standard care without the medication. The study will follow these participants over a period of three months to assess the incidence of central pain development in both groups. This approach seeks to determine if early intervention with Pregabalin can mitigate pain outcomes in SCI patients.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Up to 3 months following traumatic or non-traumatic SCL
* Ability to give informed consent and cooperate

Exclusion Criteria:

* Pregnancy
* Neurological or other medical conditions that may interfere with sensation
* Neuropathic-like pain before recruitment (described as painful sensation of electric current, burning, numbness, tingling, pricking, or squeezing)
* Being treated with Pregabalin
* Blood creatinine levels \>1.2 or creatinine clearance \<60
* Sensitivity to lactose

Where it's running

• Loewenstein Rehabilitation Hospital
  Raanana, Israel Recruiting

Study contacts

• Principal investigator: Amiram Catz, Catz — Loewenstein Rehabilitation Hospital
• Study coordinator: Amiram Catz, Prof.
• Email: amiramc@clalit.org.il
• Phone: 972-9-770-9934

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.