Non-invasive spinal stimulation combined with gait training to improve walking after incomplete spinal cord injury

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Participants complete gait rehabilitation sessions with and without transcutaneous spinal cord stimulation (tSCS) to identify the most effective stimulation settings. Clinical outcomes include neurological level and motor/sensory function using ASIA/ISNCSCI, walking measures such as the 10-meter walk test and WISCI II, and spasticity via the Modified Ashworth Scale. Optional neurophysiological tests (F- and H-waves, TMS-evoked MEPs, and surface EMG) will probe spinal excitability and corticospinal conduction to explore underlying mechanisms. The protocol compares functional and physiological changes after gait training with tSCS versus gait training alone to determine whether tSCS facilitates lower-limb strength and gait recovery.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Male or female more than 18 years old;
* With a stable traumatic o nor traumatic incomplete motor cervical or thoracic SCI;
* Time since SCI more than 6 months;
* American Spinal Injury Association Impairment Scale (AIS)-D who could realize gait at least 6 meters with or without technical help;
* Capacity for compression the nature of the study and signed informed consent.

Exclusion Criteria:

* Unstable medical condition (cancer, acute infections, etc.);
* Severe spasticity (≥ 3 score on the Modified Ashworth scale (MAS)),
* Peripheral nerve affectation;
* Ulcers on the electrode applied area;
* Intolerance of tSCS.

Where it's running

• Institut Guttmann
  Badalona, Barcelona, Spain Recruiting

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.