Condition

Hemorrhage clinical trials and research

• 19Clinical trials
• 144NIH research projects
• 11Countries

Newest Hemorrhage clinical trials

All recruiting trials (19)

• Simplified Tranexamic Acid Regimen for Trauma with Hemorrhage

  This trial tests a simplified TXA dosing approach to see if it safely helps adults with major trauma and significant bleeding.

  Recruiting at 3 sites Phase 4 Second Affiliated Hospital, Zhejiang University, School of Medicine · Hangzhou, Zhejiang and 2 other locations · NCT07869537

• Bleeding control after single-ray amputation: Hemocoll vs Avitene vs bone wax

  This trial tests whether Hemocoll, Avitene, or bone wax better stop bleeding from exposed bone after a planned single-ray amputation in adults.

  Recruiting at 3 sites Adichunchanagiri Institute of Medical Sciences, B G Nagara · Kolār, Karnataka and 2 other locations · NCT07788846

• Tailored lower‑intensity blood thinner plan after left atrial appendage closure to prevent stroke

  This project tests whether people with non‑valvular atrial fibrillation who get a left atrial appendage closure can stop blood thinners after taking low‑dose apixaban (2.5 mg twice daily) for 3 months, compared with people who stay on standard‑dose DOACs.

  Recruiting National Medical Research Center for Therapy and Preventive Medicine · Moscow · NCT07575867

• Catheter ablation plus LAAC vs anticoagulation in frail elderly A-fib patients

  This study tests whether adding left atrial appendage closure to ablation is as good as using long-term blood thinners in frail people aged 75 and up with atrial fibrillation.

  Recruiting Guangdong Provincial People's Hospital · Guangzhou, Guangdong · NCT07441382

• Preventing pneumonia after brain hemorrhage with extra mouth care and preventive antibiotics

  This will test whether enhanced oral hygiene combined with preventive antibiotics can help adults who recently had a spontaneous intracerebral hemorrhage avoid pneumonia.

  Recruiting Phase 4 Beijing Tiantan Hospital · Beijing, Beijing Municipality · NCT07311343

• Comparing tranexamic acid dosing during heart surgery with cardiopulmonary bypass

  This research will test whether three different tranexamic acid dosing schedules keep fibrinolysis suppressed longer and limit bleeding in adults having elective heart surgery with cardiopulmonary bypass.

  Recruiting University of Ioannina · Ioannina · NCT07164300

• Tranexamic acid to reduce bleeding in sleeve gastrectomy and mini gastric bypass

  This trial will test whether giving tranexamic acid before laparoscopic sleeve gastrectomy or mini gastric bypass reduces bleeding in adults with morbid obesity.

  Recruiting Phase 4 Patel Hospital, Pakistan · Karachi, Sindh · NCT07098780

• Q Therapeutic System to improve arm and hand function after chronic stroke

  This trial will try the Q Therapeutic (BQ 3.0) electromagnetic stimulation system with guided arm exercises to see if it improves upper limb function in people 6 months to 5 years after a stroke.

  Recruiting Burke Rehabilitation Hospital · White Plains, New York · NCT06979466

• Tranexamic acid to reduce bleeding during second-trimester dilation and evacuation

  We will test whether giving prophylactic tranexamic acid before a second-trimester dilation and evacuation reduces bleeding for people aged 18 and older at 18–24 weeks of pregnancy.

  Recruiting at 3 sites Phase 4 University of California, San Diego · San Diego, California and 2 other locations · NCT06820177

• Evaluating Onyx™ Liquid Embolic System for treating active arterial bleeding

  This study is testing whether the Onyx™ Liquid Embolic System can safely and effectively stop active bleeding in patients with peripheral artery issues.

  Recruiting at 20 sites Medtronic Endovascular · Phoenix, Arizona and 19 other locations · NCT06742801

• Investigating adverse drug events in patients taking blood thinners in the emergency department

  This study looks at how often patients on blood thinners experience problems like bleeding or blood clots when they come to the emergency room.

  Recruiting Centre Hospitalier Universitaire de Besancon · Besançon · NCT06692504

• Comparing TachoSil and Surgicel Original to control mild-to-moderate soft tissue bleeding during open surgery

  This test compares TachoSil and Surgicel Original to see which stops mild-to-moderate soft tissue bleeding better during certain elective open surgeries.

  Recruiting at 9 sites Phase 3 Corza Medical GmbH · Torrance, California and 8 other locations · NCT06664775

• Reducing postpartum blood loss with coagulation factor XIII

  This study is testing if giving a treatment called coagulation factor XIII can help reduce heavy bleeding after childbirth in women who have had a vaginal delivery.

  Recruiting at 8 sites Phase 4 University of Zurich · Geneva, Canton of Geneva and 8 other locations · NCT06481995

• Monitoring blood flow during surgery for craniosynostosis

  This study is testing new ways to monitor blood flow during surgery for craniosynostosis in infants to see if they can make the procedure safer and more effective.

  Recruiting IRCCS Azienda Ospedaliero-Universitaria di Bologna · Bologna, BO · NCT06263075

• Assessing oxytocin's effect on bleeding during second trimester procedures

  This study is testing if giving oxytocin during certain medical procedures can help reduce bleeding for pregnant women who are 18 weeks along or more.

  Recruiting Phase 2 University of Colorado, Denver · Denver, Colorado · NCT06141447

• Calcium and vasopressin treatment for trauma patients at risk of shock

  This study is testing if giving calcium and vasopressin to trauma patients at risk of shock can help them recover better and faster.

  Recruiting at 18 sites Phase 2 University of Pittsburgh · Chandler, Arizona and 17 other locations · NCT05958342

• A large biobank for acute and emergency medicine

  This study is collecting health information and samples from patients with sudden illnesses in the Emergency Department to see if it can help improve treatments and predict how patients will do.

  Recruiting University Medical Center Groningen · Groningen · NCT04615065

• Understanding how drugs work in children

  This study is trying to find the best and safest doses of certain medications for children and young adults under 21 who are being treated for conditions like COVID-19 and pulmonary arterial hypertension.

  Recruiting at 5 sites Duke University · Phoenix, Arizona and 51 other locations · NCT04278404

• Monitoring brain blood flow and oxygen in premature infants

  This study is trying to see if monitoring blood flow and oxygen in the brains of premature infants with certain types of brain bleeding can help doctors understand how serious their condition is and how well treatments are working.

  Recruiting Boston Children's Hospital · Boston, Massachusetts and 2 other locations · NCT02601339

NIH-funded research (newest 40 of 144)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Wearable tech to track blood loss during childbirth

  A wearable device monitors cardiovascular signals to detect postpartum hemorrhage early so clinicians can act quickly to protect mothers.

  NIH research Washington University · Saint Louis, United States · NIH-11627926

• SATURN MRI ancillary study: statins after intracerebral hemorrhage and brain MRI markers

  This study looks at what happens to brain MRI markers and health outcomes when people with a specific type of brain bleed continue or stop taking statins.

  NIH research Beth Israel Deaconess Medical Center · Boston, United States · NIH-11625633

• Statin use after brain bleed MRI study in ICH patients (SATURN MRI) Ancillary Study

  This project tests whether continuing or stopping statin therapy after an intracerebral hemorrhage affects brain changes seen on MRI and related health outcomes in people with lobar ICH.

  NIH research Beth Israel Deaconess Medical Center · Boston, United States · NIH-11625632

• Statin use after brain bleed: SATURN MRI ancillary study

  This project tests whether continuing statin medicines after a brain bleed (lobar intracerebral hemorrhage) affects new brain blood vessel findings and long-term health.

  NIH research Beth Israel Deaconess Medical Center · Boston, United States · NIH-11625628

• Maternal Postpartum Monitoring with a Wearable Sensor (MOMS)

  A wearable system called MOMS will continuously monitor multiple physiological signals in pregnant people to detect postpartum hemorrhage earlier than standard vital signs.

  NIH research University of California-Irvine · Irvine, United States · NIH-11536966

• Anticoagulation in ICH Survivors with Atrial Fibrillation and Small Vessel Disease

  This project looks at how to safely use blood-thinning medicines in people who survived a brain bleed and also have atrial fibrillation and small vessel disease.

  NIH research Yale University · New Haven, United States · NIH-11533213

• Statin use after lobar intracerebral hemorrhage

  This trial compares continuing versus stopping statins in people who had a lobar intracerebral hemorrhage to see how that affects repeat brain bleeds, strokes, heart attacks, and recovery over two years.

  NIH research Beth Israel Deaconess Medical Center · Boston, United States · NIH-11518526

• Statin use after lobar brain hemorrhage

  This trial compares stopping versus continuing statin medicine in people who had a lobar brain bleed to learn effects on repeat bleeding and future heart or stroke events.

  NIH research Beth Israel Deaconess Medical Center · Boston, United States · NIH-11518525

• Cognitive screening after an aneurysmal brain bleed

  Using patient questionnaires to find thinking and memory problems in people recovering from aneurysmal subarachnoid hemorrhage.

  NIH research University of Texas Hlth Sci Ctr Houston · Houston, United States · NIH-11468520

• Blood test to predict delayed brain injury after an aneurysm bleed

  This project is creating a blood test to spot which people who had a brain aneurysm bleed are likely to develop delayed brain injury in the days after the bleed.

  NIH research University of Texas Hlth Sci Ctr Houston · Houston, United States · NIH-11467911

• Hemostatic B-knob Microgels for Pediatric Bleeding

  A kid-friendly hemostatic therapy using age-tuned microgels to stop dangerous bleeding after injury in children.

  NIH research North Carolina State University Raleigh · Raleigh, United States · NIH-11463381

• Blocking red blood cell death after brain hemorrhage

  A study at Yale is exploring whether stopping a specific kind of red blood cell death after a brain hemorrhage could improve recovery.

  NIH research Yale University · New Haven, United States · NIH-11450183

• AI-powered real-time postpartum hemorrhage risk predictor in clinical care

  A real-time AI tool integrated into electronic health records helps identify women at risk for postpartum hemorrhage so clinicians can intervene earlier.

  NIH research Brigham and Women's Hospital · Boston, United States · NIH-11448238

• RBC transfusion for brain bleed patients with intracranial hemorrhage

  A small, early-stage study will look at whether providing specific red blood cell transfusions helps people who have an intracranial hemorrhage recover better.

  NIH research Columbia University Health Sciences · New York, United States · NIH-11445366

• Targeting Ubiquitination to Improve Uterotonic Therapies in Postpartum Hemorrhage

  A new approach aims to boost uterine contractions during childbirth and after delivery by understanding how a hormone receptor is regulated, potentially reducing postpartum hemorrhage risk.

  NIH research Washington University · Saint Louis, United States · NIH-11442951

• Personalized Postpartum Bleeding Risk Prediction with Machine Learning and Genetic Scores

  This grant aims to create a personalized tool that predicts a mother’s risk of postpartum hemorrhage using machine learning and her genetic information.

  NIH research Brigham and Women's Hospital · Boston, United States · NIH-11419168

• OPTIMUM OB-TXA: Timing, route, and dose of tranexamic acid to prevent postpartum bleeding before cord clamping

  Aims to find the best time, method, and amount of tranexamic acid given before cord clamping to prevent postpartum hemorrhage in new mothers and protect babies.

  NIH research Inova Health Care Services · Fairfax, UNITED STATES · NIH-11404879

• Criteria for Retriage to Improve Trauma-Related Bleeding and Survival

  Aimed at improving how injured patients with serious bleeding are moved to high-level trauma centers to receive fast, life-saving care.

  NIH research Northwestern University · Chicago, United States · NIH-11402536

• Statin use in brain bleed patients MRI study in SATURN MRI ancillary

  A large MRI-focused study will look at whether continuing statin therapy after a brain bleed helps or harms patients who had lobar intracerebral hemorrhage.

  NIH research Beth Israel Deaconess Medical Center · Boston, United States · NIH-11400999

• 3D brain blood vessel model to study subarachnoid hemorrhage and test therapies

  A researcher will develop a 3D printed, biomimetic brain model to study subarachnoid hemorrhage and screen potential nanoparticle-based treatments.

  NIH research Vanderbilt University Medical Center · Nashville, United States · NIH-11400496

• Stanford PRIHSM: Improving urgent maternal care in Alabama’s maternity deserts

  A large NIH grant supports Stanford and partners in Alabama to improve access to life-saving obstetric care for pregnant people in areas with very limited maternity services.

  NIH research Stanford University · Stanford, United States · NIH-11397547

• Integrated Coagulation Sensing to Predict Bleeding and Guide Transfusions

  A patient-focused program to use a new blood-clotting profile tool (iCoagLAB) to help doctors predict bleeding risk and guide transfusion decisions for people on ECMO.

  NIH research Massachusetts General Hospital · Boston, United States · NIH-11397226

• Statin effects on brain scans after lobar brain hemorrhage

  This project compares keeping versus stopping statin medicines in people who had lobar intracerebral hemorrhage to see how their brain scans change over two years.

  NIH research Beth Israel Deaconess Medical Center · Boston, United States · NIH-11396153

• Statins after lobar brain hemorrhage — MRI monitoring

  This project compares continuing versus stopping statin medicines in people who had a lobar brain bleed to see how small-bleed markers on brain MRI change over two years.

  NIH research Beth Israel Deaconess Medical Center · Boston, United States · NIH-11396143

• Statin use after intracerebral hemorrhage with MRI follow-up

  This research compares continuing versus stopping statin medicines after lobar intracerebral hemorrhage to see how they affect MRI signs of brain bleeding and small vessel disease in people who were already taking statins.

  NIH research Beth Israel Deaconess Medical Center · Boston, United States · NIH-11396134

• AI-powered CT tools to speed up bleeding diagnosis after torso injuries

  A computer-assisted CT tool helps doctors quickly find and treat life-threatening torso bleeding based on whole-body scans.

  NIH research University of Maryland Baltimore · Baltimore, United States · NIH-11392336

• Shape Memory Foam Dressings to Stop Bleeding after Injury

  A promising foam dressing made from shape memory polymers is being developed to quickly stop bleeding from traumatic wounds, even in remote settings.

  NIH research Texas Engineering Experiment Station · College Station, United States · NIH-11390597

• Targeting HDAC3 to reduce brain damage after a brain bleed

  This project will test whether blocking a protein called HDAC3 can reduce inflammation and improve recovery after an intracerebral hemorrhage (brain bleed).

  NIH research Augusta University · Augusta, United States · NIH-11386398

• Biomarkers to Fine-Tune Intrathecal Nicardipine for Brain Bleeding-Related Stroke

  Researchers are testing biomarkers to personalize intrathecal nicardipine treatment for patients after subarachnoid hemorrhage to prevent brain damage.

  NIH research Emory University · Atlanta, United States · NIH-11385464

• Understanding and preventing life-threatening lung bleeding in lupus patients

  A new NIH grant is exploring why some lupus patients develop dangerous lung bleeding and how we might predict and prevent it.

  NIH research University of Florida · Gainesville, United States · NIH-11385326

• Nebulized Tranexamic Acid to Stop Pediatric Tonsil Bleeding after Surgery

  A pediatric-focused study tests a breathing spray of tranexamic acid to help kids stop bleeding after tonsil surgery without another operation.

  NIH research University of Texas Hlth Science Center · San Antonio, United States · NIH-11381020

• Silent brain injuries after brain bleed may predict dementia risk

  A study using MRI and cognitive tests to see if hidden brain injuries after spontaneous intracerebral hemorrhage help forecast later cognitive decline.

  NIH research Rush University Medical Center · Chicago, United States · NIH-11380839

• Adropin as a shield for the brain after a brain hemorrhage

  A potential treatment with adropin is being studied to protect brain cells after a subarachnoid hemorrhage and reduce stroke-like damage.

  NIH research University of Florida · Gainesville, United States · NIH-11380727

• Tracking how stem cells and their tiny vesicles move in a mouse model of brain bleed

  A study in mice will map how stem cells and their extracellular vesicles distribute in the brain after an intracerebral hemorrhage to better understand how they could help repair the damaged brain.

  NIH research University of Miami School of Medicine · Coral Gables, United States · NIH-11380600

• Hemorrhage and blood vessel health after injury: how red cells and endothelium work together

  A large NIH grant is exploring how red blood cells and the lining of blood vessels interact after injury to improve bleeding control and outcomes.

  NIH research University of Cincinnati · Cincinnati, United States · NIH-11375950

• Manganese-based compound as a potential therapy for subarachnoid hemorrhage

  A new manganese porphyrin-based drug is being explored as a possible treatment to reduce brain injury after a subarachnoid hemorrhage.

  NIH research Barrow Neurological Institute at St. Joseph's Hospital and Medical Center · Phoenix, United States · NIH-11373497

• Calcium given during cesarean to reduce severe bleeding

  A simple, patient-friendly trial will test whether giving calcium through an IV at cesarean delivery can lower the risk of heavy bleeding after birth for mothers.

  NIH research George Washington University · Washington, United States · NIH-11373268

• Simulation to strengthen obstetricians' hands-on skills for postpartum hemorrhage

  A multicenter program uses realistic obstetric simulations to help OB attendings perform critical maneuvers like Bakri balloon placement and suturing techniques during postpartum hemorrhage.

  NIH research Columbia University Health Sciences · New York, United States · NIH-11372119

• Ferroptosis and iron's role in brain cell death after newborn brain bleeding causing hydrocephalus

  This grant aims to understand how iron-driven cell death in brain support cells after severe newborn brain bleeding leads to hydrocephalus, with the goal of preventing this condition.

  NIH research Stanford University · Stanford, United States · NIH-11368897

• START Network for Promising Novel Drug Testing in Subarachnoid Hemorrhage

  A network of three sites will test two potential treatments in a late-stage, animal model study of subarachnoid hemorrhage to help improve outcomes for patients who suffer this brain injury.

  NIH research University of Florida · Gainesville, United States · NIH-11367161

Related topics

Quick answers

How many Hemorrhage clinical trials are recruiting right now?

19, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 11 countries. The most sites are in United States (8 trials), China (3 trials), France (1 trial), Greece (1 trial), Netherlands (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 4: 5, Phase 2: 2, Phase 3: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.

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