NIH-funded research R21 grant

RBC transfusion for brain bleed patients with intracranial hemorrhage

Official title: RBc transfusion Characteristics in IntraCranial Hemorrhage (RBC-ICH)

Funded at Columbia University Health Sciences · NIH-11445366 · Data updated 2026-11-12

A small, early-stage study will look at whether providing specific red blood cell transfusions helps people who have an intracranial hemorrhage recover better.

More Hemorrhage research and trials

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionColumbia University Health Sciences
NIH-funded
Lab location1 site (New York, United States)
Project startAugust 1, 2026
Project endJuly 31, 2028
Funding year2026
Award (this year)$246,750
NIH project number1R21HL189042-01
Project IDNIH-11445366 on NIH RePORTER

Who could benefit from this research

Could help

Adults with intracranial hemorrhage who have anemia or are at risk of anemia and could potentially receive RBC transfusions.

Less likely to help

Patients who do not have anemia or whose condition precludes transfusion may not benefit.

What this research studies

This project focuses on people who have a serious brain bleed and may be anemic. It explores how different red blood cell transfusion strategies could affect brain oxygen delivery and recovery after hemorrhage. The study will examine characteristics of transfused cells and donor factors to see if these influence outcomes. By understanding transfusion effects in ICH, the research could inform more personalized treatment for brain-injury patients.

Why it matters

Potential benefit: If successful, the findings could guide more effective transfusion practices to improve brain recovery after intracranial hemorrhage.

How similar studies have gone: Early data suggest transfusions may help some ICH patients, but results vary across studies and settings.

Where this research is happening

  • Columbia University Health Sciences
    New York, United States
    Active

Researchers

  • Principal investigator: Roh, David — Columbia University Health Sciences
  • Study coordinator: Roh, David

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.