A large biobank for acute and emergency medicine

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Acutelines is a prospective biobank designed to collect extensive data and biomaterials from patients presenting with a variety of acute conditions at the Emergency Department. The initiative aims to enhance the understanding of acute diseases and improve treatment outcomes through interdisciplinary research. By systematically gathering clinical data, imaging, and biomaterials over time, the project seeks to develop personalized treatment strategies and predict patient outcomes more effectively. The study employs a deferred consent procedure to facilitate data collection while ensuring patient rights are respected.

Why it matters

Who can join: the full rules

Inclusion Criteria, at least one of the following:

* Triaged as one of highest two triage categories (red or orange) according to the Manchester triage system;
* Triaged as the third highest triage category (yellow) and arrival by EMS of Helicopter Emergency Medical Service (HEMS;
* Shock
* Suspicion of sepsis (based on either physicians' suspicion, Sepsis-2 or Sepsis-3 criteria)
* Acute kidney injury (AKI)
* Anaphylactic reaction
* Syncope
* Intoxication
* Thrombosis
* Pulmonary embolism
* Bleeding while using anti-coagulant drugs
* Gastro-intestinal bleeding
* Electrolyte disturbance

Exclusion Criteria:

* Referred for organ transplantation as recipient
* Transfer from other hospital
* Accidental contact patient material (i.e. internal work-related accident)

While data- and imaging will be collected from all these patients, biomaterials will only be collected from patients fulfilling the first criterion (i.e. triaged as one of highest two triage categories \[red or orange\] according to the Manchester triage system) and from patients with shock or a suspicion of sepsis.

Where it's running

• University Medical Center Groningen
  Groningen, Netherlands Recruiting

Study contacts

• Study coordinator: Hjalmar Bouma, MD, PhD
• Email: acutelines@umcg.nl
• Phone: +31 50 361 6161

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.