Condition

Adrenal Insufficiency clinical trials and research

• 12Clinical trials
• 1NIH research projects
• 7Countries

Newest Adrenal Insufficiency clinical trials

All recruiting trials (12)

• Adrenal Function in RA Patients on Low-Dose Corticosteroids

  This study tests how common adrenal insufficiency is among rheumatoid arthritis patients who are taking low-dose corticosteroids.

  Recruiting Bursa Yuksek Ihtisas Training and Research Hospital · Bursa, Yıldırım · NCT07866326

• Normal ranges and diagnostic cut-offs for salivary cortisol

  This project will test two saliva cortisol methods — a lab LC‑MS assay and a rapid fluorescence immunoassay — to find normal ranges and the best diagnostic cut-offs for adults with suspected Cushing syndrome or adrenal insufficiency.

  Recruiting Shanghai 6th People's Hospital · Shanghai, Shanghai Municipality · NCT07168122

• Evaluating adrenal insufficiency after surgery in patients with primary aldosteronism

  This study is testing how often people with primary aldosteronism develop adrenal insufficiency after having surgery to remove their adrenal glands.

  Recruiting Chongqing Medical University · Chongqing, Chongqing Municipality · NCT06955286

• Assessing adrenal function in children with leukemia after glucocorticoid treatment

  This study is trying to see how glucocorticoid treatment affects the adrenal function in children with leukemia to better understand and manage any potential hormone problems they might have after treatment.

  Recruiting at 2 sites University Children's Hospital Basel · Aarau and 1 other locations · NCT06861530

• Treatment for adrenal insufficiency in patients with Cushing syndrome using osilodrostat

  This study is testing if the medication osilodrostat, combined with a specific dose of another steroid, can help people with Cushing syndrome avoid adrenal insufficiency while keeping their hormone levels balanced.

  Recruiting University of Michigan · Ann Arbor, Michigan · NCT06430528

• Assessing adrenal function in patients with Addison's disease

  This study is testing whether measuring a specific hormone can help doctors understand how well the adrenal glands are working in people with Addison's disease and if that can improve their treatment and quality of life.

  Recruiting Istituto Auxologico Italiano · Milan · NCT06309498

• Supplemental hydrocortisone for adrenal insufficiency during stress

  This study is testing if adding hydrocortisone can help people with polymyalgia rheumatica or giant cell arteritis who have low adrenal function feel better during stressful times compared to a placebo.

  Recruiting at 3 sites Phase 4 Copenhagen University Hospital, Rigshospitalet · Aarhus and 2 other locations · NCT05435781

• Hydrocortisone vs. placebo for adrenal insufficiency symptoms after stopping glucocorticoids

  This study is testing if hydrocortisone can help people over 50 feel better after stopping glucocorticoids and dealing with adrenal insufficiency symptoms.

  Recruiting at 3 sites Phase 4 Odense University Hospital · Aarhus and 2 other locations · NCT05193396

• Determining accurate cortisol levels for diagnosing adrenal insufficiency

  This study is testing new ways to measure cortisol levels in people to see if it helps doctors better diagnose adrenal insufficiency.

  Recruiting Montefiore Medical Center · The Bronx, New York · NCT05149638

• Circadian Gene Changes in People with Glucocorticoid Disorders

  This study tests whether circadian gene expression in blood cells differs between people with glucocorticoid disorders and healthy controls.

  Recruiting University of Roma La Sapienza · Roma, Roma · NCT04374721

• Understanding how drugs work in children

  This study is trying to find the best and safest doses of certain medications for children and young adults under 21 who are being treated for conditions like COVID-19 and pulmonary arterial hypertension.

  Recruiting at 5 sites Duke University · Phoenix, Arizona and 51 other locations · NCT04278404

• Evaluation of children with endocrine and metabolic conditions

  This study is testing how endocrine and metabolic disorders affect children from 3 months to 18 years old by looking at their medical history and physical exams, and it may involve family members in genetic testing to help with diagnosis.

  Recruiting National Institutes of Health Clinical Center (CC) · Bethesda, Maryland · NCT02769975

NIH-funded research (1)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Investigating adrenal insufficiency as a risk factor for sepsis

  This study is looking at how low levels of certain hormones from the adrenal glands might affect people with sepsis, a serious illness, to see if better treatments can be developed to help them recover.

  NIH research University of Kentucky · Lexington, United States · NIH-11075836

Related topics

Quick answers

How many Adrenal Insufficiency clinical trials are recruiting right now?

12, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 7 countries. The most sites are in United States (4 trials), Denmark (2 trials), China (2 trials), Italy (2 trials), Turkey (Türkiye) (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 4: 2. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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