Tranexamic acid to reduce bleeding in sleeve gastrectomy and mini gastric bypass

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a randomized, placebo-controlled Phase 4 trial comparing tranexamic acid given before surgery versus placebo in adults undergoing laparoscopic sleeve gastrectomy (LSG) or mini gastric bypass (MGB). Participants are randomized to receive either tranexamic acid or normal saline before their operation and then undergo standard perioperative care. Investigators will measure intraoperative blood loss, postoperative hemoglobin levels, and monitor for bleeding-related complications and other adverse events. The trial is conducted at a single site (Patel Hospital, Karachi) and excludes patients on anticoagulants, with bleeding disorders, or with known TXA allergy.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients above 18 years of age AND
* Undergoing Laparoscopic Sleeve Gastrectomy and MGB
* Morbid obesity

Exclusion Criteria:

* Patients on anti-platelets/anti-coagulants
* Patients with inherited or acquired bleeding disorders
* Patients with any acute medical condition predisposing to bleeding
* Hormonal contraceptives
* Known Allery to TXA
* Female hormonal replacement therapy

Where it's running

• Patel Hospital
  Karachi, Sindh, Pakistan Recruiting

Study contacts

• Study coordinator: Yusra Jamshed, MBBS
• Email: yusra.j.khan@gmail.com
• Phone: +923343914332

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.