Nebulized Tranexamic Acid to Stop Pediatric Tonsil Bleeding after Surgery
Official title: TranExamic Atomized for Pediatric post-Operative Tonsillectomy hemorrhage (TEAPOT)
Funded at University of Texas Hlth Science Center · NIH-11381020 · Data updated 2026-11-12
A pediatric-focused study tests a breathing spray of tranexamic acid to help kids stop bleeding after tonsil surgery without another operation.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Texas Hlth Science Center NIH-funded |
| Lab location | 1 site (San Antonio, United States) |
| Project start | August 1, 2025 |
| Project end | July 31, 2027 |
| Funding year | 2026 |
| Award (this year) | $356,249 |
| NIH project number | 5R34HL177446-02 |
| Project ID | NIH-11381020 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates are children aged 0-11 who have post-tonsillectomy bleeding and are eligible for non-operative management.
✕Less likely to help
Children without post-tonsillectomy bleeding or those requiring immediate surgical control may not benefit.
What this research studies
This project explores using a nebulized form of tranexamic acid to treat post-tonsillectomy bleeding in children aged 0-11. By delivering medication directly to the tonsil bed through a mask or jet nebulizer, the goal is to reduce the need for a second surgery and avoid additional anesthesia and pain. The study builds on preliminary data suggesting the nebulized approach can lower surgical intervention rates while remaining safe. If successful, this could provide a non-operative option to manage bleeding and shorten recovery for kids after tonsil removal.
Why it matters
Potential benefit: If successful, children with post-tonsillectomy bleeding may avoid a second surgery and its risks, shortening recovery and reducing hospital visits.
How similar studies have gone: Preliminary data show a 44% reduction in the need for a second operation with nebulized TXA, supporting potential benefit while broader confirmation is needed.
Where this research is happening
-
University of Texas Hlth Science Center
San Antonio, United States Active
Researchers
- Principal investigator: Meyer, Andrew Duncan Joseph — University of Texas Hlth Science Center
- Study coordinator: Meyer, Andrew Duncan Joseph
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.