Condition
Gestational Diabetes clinical trials and research
As of November 12, 2026, Find a Trial lists 42 Gestational Diabetes clinical trials that are recruiting, at sites in 18 countries (most in United States (21), Malaysia (2), Singapore (2)). By phase: Early Phase 1 (3), Phase 4 (2), Phase 2 (1), Phase 3 (1). The most active sponsors are University of Iowa (3), National University of Malaysia (2), Thomas Jefferson University (2). There are also 55 NIH-funded research projects on Gestational Diabetes, with $30.2 million in listed awards. Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 42Clinical trials
- 55NIH research projects
- 18Countries
Newest Gestational Diabetes clinical trials
All recruiting trials (42)
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Early Glucose Patterns in Pregnant Women at Risk for GDM
This study tests whether continuous glucose monitoring in early pregnancy can detect dysglycemia before GDM is diagnosed, in women with and without known risk factors.
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Probiotic-augmented therapy for gestational diabetes
This trial tests whether adding multistrain probiotics to metformin, insulin, or their combination can improve blood sugar control and inflammation in pregnant women with gestational diabetes.
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Maternal insulin and fat metabolism in pregnancies at risk for preeclampsia and gestational diabetes
This project will try to see if insulin resistance and how the body burns fats early in pregnancy predict later preeclampsia or gestational diabetes in people at higher risk.
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How sleep, lifestyle, and metabolism relate to pregnancy outcomes in gestational diabetes
This project will see if sleep quality, anxiety, eating and activity habits, and metabolic markers relate to blood sugar control and birth outcomes in pregnant people with gestational diabetes.
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Pre-eclampsia risk in pregnancies after oocyte donation
We will follow pregnant women who used donated eggs and women who used their own eggs to see if pregnancies after oocyte donation lead to a higher risk of pre-eclampsia.
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Mobile-based obstetric monitoring for hypertension and diabetes during pregnancy
A mobile app-based program lets pregnant people with high blood pressure or gestational diabetes track BP and glucose at home and share results with their care team to guide care.
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Continuous glucose monitoring during late pregnancy and after delivery for gestational diabetes
This study will collect Dexcom G7 glucose data from people with gestational diabetes during the third trimester and for two weeks after birth to see if those patterns predict an abnormal 6‑week postpartum oral glucose tolerance test.
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Once-daily long-acting insulin versus long-acting plus mealtime insulin for blood sugar control in pregnancy
This trial will test whether once-daily long-acting insulin alone can control blood sugars as well as long-acting insulin plus mealtime short-acting insulin for pregnant people with gestational or type 2 diabetes.
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Real-time glucose monitoring with group support during pregnancy
This program will test whether wearing a real-time glucose monitor and joining a group chat helps pregnant people at risk for gestational diabetes keep their blood sugar in a healthy range.
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Observational study on pregnancy and future health outcomes
This study looks at how conditions like obesity and gestational diabetes during pregnancy affect the health of both mothers and their babies now and in the future.
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Delivering HOPE: healthy food and grocery support during pregnancy
This project will test whether providing pregnant people with healthy food and grocery funds during pregnancy reduces excessive weight gain compared with enhanced usual care.
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Examining how aspirin metabolism relates to metabolic dysfunction in pregnant individuals at risk of preeclampsia
This study is trying to see how the way pregnant people process aspirin relates to their metabolic health and the health of their babies, especially for those at risk of preeclampsia.
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Comparing insulin treatment with or without metformin for gestational diabetes
This study is testing if pregnant women with gestational diabetes can benefit from continuing metformin along with insulin to see if it helps them and their babies stay healthier.
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Understanding how HbA1c levels predict pregnancy complications in women with gestational diabetes
This study is trying to see if certain HbA1c levels can help predict complications during pregnancy for women with gestational diabetes.
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Understanding how growth hormone affects insulin-producing cells in women with gestational diabetes
This study looks at how growth hormone affects insulin-producing cells in women who had gestational diabetes compared to those who didn't, to see if it helps us understand their risk for type 2 diabetes.
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Investigating the role of endothelin-1 in blood vessel function after gestational diabetes
This study is testing how a substance called endothelin-1 affects blood vessel function in women who had gestational diabetes to see if insulin can help improve their heart health after pregnancy.
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Comparing early and late blood glucose monitoring in pregnant women with a history of gestational diabetes
This study tests if pregnant women with a history of gestational diabetes do better when they monitor their blood sugar early in pregnancy instead of waiting until later.
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Understanding Gestational Diabetes in Asian Pregnant Women
This study is trying to learn more about gestational diabetes in Asian pregnant women to see how different types of the condition affect their health and treatment options.
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Nutrition and community food support for postpartum recovery after gestational diabetes
This project will test whether a culturally tailored medically provided meal program that lets new mothers switch from prepared to fresh meals helps Black women with obesity who had gestational diabetes manage their weight and diet after childbirth.
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Comparing strict and permissive thresholds for treating gestational diabetes
This study is testing whether treating gestational diabetes with stricter or more relaxed blood sugar targets leads to better health outcomes for mothers and their babies.
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Comparing strict and permissive thresholds for treating gestational diabetes
This study tests whether starting treatment for gestational diabetes with stricter or more relaxed rules leads to better health outcomes for moms and their babies.
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Monitoring glucose levels in pregnant women to improve gestational diabetes diagnosis
This study is testing if using a continuous glucose monitor can help better diagnose gestational diabetes in pregnant women of Chinese and Indian descent.
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Using continuous glucose monitoring for women with gestational diabetes
This study is testing whether using a continuous glucose monitor can help women with gestational diabetes manage their blood sugar better during and after pregnancy compared to regular blood sugar checks.
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Peking University Weifang Birth Cohort
This project will follow pregnant women in Weifang and their children to see if pre-pregnancy and prenatal exposures affect maternal and child health up to age 18.
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Home-based diabetes screening for women after gestational diabetes
This study is testing if having community health workers do diabetes tests at home can help women who had gestational diabetes get screened for diabetes more easily after giving birth.
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Monitoring glucose levels in women after gestational diabetes
This study is testing if wearing a continuous glucose monitor can help women who had gestational diabetes keep track of their blood sugar levels after giving birth.
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Improving oral health during pregnancy to prevent complications
This study tests if treating gum disease in pregnant women can help their babies grow better and lower the chances of early delivery.
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Investigating oxidative stress and blood vessel function in women with a history of gestational diabetes
This study is trying to see how oxidative stress affects blood vessel function in women who had gestational diabetes in the past five years.
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Using metformin to improve blood vessel function in women after gestational diabetes
This study is testing if metformin can help improve blood vessel health in women who had gestational diabetes to reduce their risk of heart problems later on.
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Randomized comparison of immediate in-hospital 2-hour OGTT versus standard 4–12 week postpartum 2-hour OGTT for people with gestational diabetes
This will test whether doing a 2-hour OGTT before hospital discharge gets more people who had gestational diabetes screened for diabetes than the usual 4–12 week outpatient test.
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Examining how exenatide works in pregnant women with gestational diabetes
This study is testing how well the diabetes drug exenatide works in pregnant women with gestational diabetes to see if it can help control their blood sugar levels better.
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Comparing 1 vs 2 Hours Post Meal Glucose Monitoring in Gestational Diabetes
This study is testing whether checking blood sugar levels 1 hour or 2 hours after meals helps pregnant women with gestational diabetes manage their condition better.
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Comparing glycemic targets in overweight and obese women with gestational diabetes
This study tests whether setting stricter blood sugar goals during pregnancy helps overweight and obese women with gestational diabetes have better outcomes for themselves and their babies.
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Comparing Insulin Detemir and NPH for Managing Diabetes in Pregnancy
This study is testing whether insulin detemir or NPH is better for managing blood sugar in pregnant women with diabetes and if it affects the risk of low blood sugar in their newborns.
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Preventing postpartum diabetes in women with gestational diabetes
This study is testing whether special support and encouragement can help women who had gestational diabetes avoid developing type 2 diabetes after giving birth.
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Early gestational diabetes management strategy compared to late management
This trial tests whether starting diabetes management earlier in pregnancy (when fasting glucose is 5.1–6.1 mmol/L) improves outcomes for women with early gestational diabetes.
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Observing gestational diabetes in pregnant women
This study looks at how common gestational diabetes is in pregnant women and what factors may increase the risk, aiming to improve care for moms and their babies.
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Using iGlucose Device to Improve Blood Sugar Management in Pregnant Women with Diabetes
This study is testing if using the iGlucose device can help pregnant women with diabetes better manage their blood sugar levels compared to regular care.
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Testing glucose tolerance right after childbirth
This study is trying to see if testing blood sugar right after childbirth can help women with gestational diabetes get better care and catch any ongoing issues sooner than the usual test done six weeks later.
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Investigating the effects of iron supplementation on glucose metabolism during pregnancy
This study is testing if taking iron supplements can help pregnant women with gestational diabetes and low iron levels manage their blood sugar better.
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Investigating early life environmental impacts on health in Shenzhen
This study is trying to see how the environment during pregnancy affects the health of mothers and their children in Shenzhen, China, over seven years.
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Effects of Metformin on Pregnancy Outcomes in Gestational Diabetes
This study tests if taking metformin along with diet and lifestyle changes can improve pregnancy outcomes for women with gestational diabetes and their babies.
NIH-funded research (newest 40 of 55)
Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.
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Digital twins of the hypothalamus, placenta, and gut to help manage gestational diabetes
A study using computer-based models of a pregnant person’s brain, placenta, and gut to better understand how gestational diabetes develops and how to tailor treatments.
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IGF factors and binding proteins in gestational diabetes and fetal growth
A study in pregnant people looks at how insulin-like growth factors and their binding proteins affect gestational diabetes and how a baby grows.
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STRONG group prenatal care to reduce gestational diabetes in American Samoa
A Yale-led program tests a group prenatal care approach to lower gestational diabetes among pregnant Pacific Islander women in American Samoa.
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Pancreatic beta cells, oxidative stress, and gestational diabetes
A study is exploring how oxidative stress and changes in pancreatic beta cells during pregnancy may contribute to gestational diabetes and future diabetes risk for both mother and baby.
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NDPP-MAP: A tailored online-hybrid program to reduce long-term health risks after pregnancy with gestational diabetes
A patient-friendly program adapts a proven diabetes prevention approach to help women who had gestational diabetes lower their risk of type 2 diabetes and heart problems.
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In Vivo Look at Placental Blood Flow in Gestational Diabetes
A non-invasive MRI study in pregnant people with gestational diabetes and those without will map how placental blood vessels work and relate to baby outcomes.
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Metformin use in gestational diabetes and its effects on child health
A long-term study will follow children whose mothers were treated with metformin during gestational diabetes to see how it may affect their health as they grow.
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Promoting better glucose control for gestational diabetes with mindfulness during pregnancy
A mindfulness-based program called EMPOWER will be developed and tested to help pregnant women with gestational diabetes manage glucose and improve health for both mom and baby.
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Islet Function in Gestational Diabetes
A study at Mayo Clinic Rochester will look at how pancreatic islet cells behave in pregnancy women with gestational diabetes and compare them to those without the condition to understand why many develop type 2 diabetes later.
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CREBRF genetics, early-life body size, and gestational diabetes in American Samoa
Aimed at understanding why childhood obesity develops in American Samoa by studying genetics and early body size using metabolomics.
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How Medicaid Postpartum Coverage and PPD Screening Could Improve Diabetes and Blood Pressure Care After Birth
A large NIH grant is studying how extending Medicaid after birth and mandating postpartum depression screening affect care for women with gestational diabetes and pregnancy-related high blood pressure.
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HIV, gestational diabetes, and TB in pregnancy
This project looks at how HIV, gestational diabetes, and tuberculosis risk intersect during pregnancy to understand how to protect mothers and babies.
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Placental Hormones and a sugar tag in Gestational Diabetes
A researcher is studying how placental hormones and a sugar-related modification in the placenta might contribute to gestational diabetes and its impact on mom and baby.
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Oxidative stress and tiny blood vessels after gestational diabetes
This study looks at why women who had gestational diabetes may have higher risk of heart and diabetes problems, by checking how oxidative stress affects tiny blood vessels.
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Why gestational diabetes risk varies among Asian American pregnant people
This project looks at how metabolism, lifestyle, and social factors relate to gestational diabetes risk in Asian American pregnant people.
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Decoding how gestational diabetes links to future coronary artery disease
A study using health records and big data to understand why women who had gestational diabetes later face heart disease, with the goal of guiding prevention.
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Fetal Brain MRI to predict how children will develop if their mother has diabetes
This project uses fetal brain imaging and related biomarkers to help identify early signs of neurodevelopmental issues in children born to mothers with diabetes.
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Glycemic checks in pregnancy using A1C to diagnose gestational diabetes
This project tests whether adjusting A1C, a common blood test, can accurately diagnose gestational diabetes during pregnancy in place of the current test methods.
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Low adiponectin in pregnancy and gestational diabetes
This work looks at how low levels of the fat‑cell hormone adiponectin in early pregnancy may lead to gestational diabetes in pregnant people.
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How a mother's obesity or gestational diabetes before birth affects a child's metabolism and brain as they grow
Researchers will follow children whose mothers had obesity or gestational diabetes during pregnancy to track changes in metabolism and brain function from childhood through adolescence.
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When to start medicine for gestational diabetes
This project compares starting diabetes medicine earlier versus later in pregnancy to see which approach leads to better health for pregnant people with gestational diabetes.
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IGF factors and binding proteins in gestational diabetes and fetal growth
This research looks at how placental IGF binding proteins may influence gestational diabetes and fetal growth, aiming to understand why some pregnancies are more risk-prone.
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Lowering the chance of type 2 diabetes after gestational diabetes
This project looks at how neighborhood conditions and public policies might help lower the chance of type 2 diabetes for women who had high blood sugar during pregnancy.
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Blood marker for beta cell loss that predicts type 2 diabetes after gestational diabetes
This project uses a blood test after pregnancy to help tell women who had gestational diabetes whether they are likely to develop type 2 diabetes.
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How diabetes medicines during pregnancy affect long-term health of moms and children
This project follows mothers treated with insulin, metformin, or glyburide for gestational diabetes and their children to track health outcomes over many years.
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Understanding how gestational diabetes and depression during pregnancy affect mothers and their children
This project explores how gestational diabetes and depression during pregnancy might influence a mother's mental health after birth and her child's brain development.
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How a Samoan gene (CREBRF) relates to early childhood body size and metabolism
This project looks at how a common Samoan gene variant called CREBRF shapes babies' and children's body size and metabolism to help explain higher obesity but lower diabetes risk in this population.
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How extended Medicaid and required postpartum depression screening affect care after pregnancies with gestational diabetes or high blood pressure
This project compares Louisiana (which extended Medicaid coverage and requires postpartum depression screening) to Mississippi to see if longer coverage and required screening improve blood sugar, blood pressure, and mood follow-up for people who had gestational diabetes or pregnancy-related high blood pressure.
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Understanding Placental Hormones and Gestational Diabetes
This work explores how hormones from the placenta and a process called O-GlcNAcylation contribute to gestational diabetes, aiming to find new ways to help mothers and babies.
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Understanding how stress affects small blood vessels after gestational diabetes
This research explores how stress in tiny blood vessels might connect gestational diabetes to a higher chance of heart disease and type 2 diabetes in women.
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Better Blood Sugar Goals for Pregnant Women with Gestational Diabetes Who Are Overweight or Obese
This project looks at whether stricter blood sugar goals can help pregnant women who have gestational diabetes and are also overweight or obese have healthier pregnancies and babies.
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HIV, pregnancy diabetes, and tuberculosis risk during pregnancy
This project looks at how HIV and gestational diabetes affect a pregnant woman's immune response to tuberculosis.
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Understanding childhood obesity and its causes in American Samoa
This study is looking at what causes childhood obesity in infants and young kids from American Samoa, especially how genes and metabolism play a role, so we can find ways to help them stay healthy from an early age.
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Understanding how gestational diabetes develops during pregnancy
This study is looking at how the body's insulin-producing cells change in pregnant women to better understand gestational diabetes and help improve diabetes care for moms both during and after pregnancy.
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Finding ways to reduce diabetes risks for women after pregnancy complications.
This study is looking at how different racial and ethnic groups, especially women of color, are affected by diabetes after having gestational diabetes, and it aims to find ways to improve health support for these women during their recovery after pregnancy.
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Improving gestational diabetes diagnosis using blood tests.
This study is looking to make it easier and more accurate to diagnose gestational diabetes in pregnant women by improving how we use blood tests, so expectant moms can have a better experience and get the right care.
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How maternal obesity and diabetes during pregnancy affect children's health as they grow up
This study looks at how a mother’s weight and diabetes during pregnancy might affect her child's health as they grow up, especially regarding weight and diabetes risk, and it aims to find ways to help kids who might be at risk.
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Understanding the risk of gestational diabetes in Asian Americans
This study is looking into why Asian American women are more likely to develop gestational diabetes during pregnancy compared to other groups, and it aims to find out the biological and social reasons behind this difference to help improve health for these moms-to-be.
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Investigating the best timing for starting medication in pregnant women with gestational diabetes
This study is looking at the best time to start medication for pregnant women with gestational diabetes when diet and exercise aren't enough, to help improve health for both moms and babies while also considering their emotional well-being.
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The effects of gestational diabetes and maternal depression on child development
This study looks at how having gestational diabetes and feeling depressed during pregnancy might affect how children develop, and it’s for moms-to-be who want to understand how their health can impact their little ones.
Related topics
Quick answers
How many Gestational Diabetes clinical trials are recruiting right now?
42, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 18 countries. The most sites are in United States (21 trials), Malaysia (2 trials), Singapore (2 trials), China (2 trials), Denmark (2 trials). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Early Phase 1: 3, Phase 4: 2, Phase 2: 1, Phase 3: 1. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.