Understanding how gestational diabetes and depression during pregnancy affect mothers and their children
Official title: Gestational Diabetes Mellitus, Perinatal Depression, and Offspring Neurodevelopmental Phenotype
Funded at New York University School of Medicine · NIH-11178601 · Data updated 2026-11-12
This project explores how gestational diabetes and depression during pregnancy might influence a mother's mental health after birth and her child's brain development.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | New York University School of Medicine NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | August 1, 2023 |
| Project end | July 31, 2026 |
| Funding year | 2025 |
| Award (this year) | $248,999 |
| NIH project number | 5R00HD103910-05 |
| Project ID | NIH-11178601 on NIH RePORTER |
Who could benefit from this research
✓Could help
This research is relevant for pregnant women who experience gestational diabetes or depression, and their children from birth through toddlerhood.
✕Less likely to help
Patients not experiencing gestational diabetes or prenatal depression would not directly benefit from this specific research focus.
What this research studies
We are looking into the connections between gestational diabetes and depression during pregnancy, which are common conditions affecting many women. Our goal is to understand how these conditions might impact a mother's mental well-being after childbirth and how they could shape her baby's brain function and development as a toddler. We hope to uncover the specific biological and behavioral pathways involved, especially considering that these conditions can disproportionately affect women from diverse backgrounds.
Why it matters
Potential benefit: This work could help us better identify mothers and children at risk, leading to earlier support and interventions for both maternal mental health and child neurodevelopment.
How similar studies have gone: Previous studies have independently linked gestational diabetes and prenatal depression to adverse outcomes in mothers and children, but this work aims to understand the combined pathways.
Where this research is happening
-
New York University School of Medicine
New York, United States Active
Researchers
- Principal investigator: Shuffrey, Lauren Christine — New York University School of Medicine
- Study coordinator: Shuffrey, Lauren Christine
Related research
Other NIH-funded projects on the same topics.
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The effects of gestational diabetes and maternal depression on child development
This study looks at how having gestational diabetes and feeling depressed during pregnancy might affect how children develop, and it’s for moms-to-be who want to understand how their health can impact their little ones.
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How gestational diabetes and depression affect mothers and their children's brain development
This study is looking at how gestational diabetes and prenatal depression can affect a mom's mental health and the brain development of her baby, with the goal of finding ways to better support moms and their little ones.
-
In Vivo Look at Placental Blood Flow in Gestational Diabetes
A non-invasive MRI study in pregnant people with gestational diabetes and those without will map how placental blood vessels work and relate to baby outcomes.
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Decoding how gestational diabetes links to future coronary artery disease
A study using health records and big data to understand why women who had gestational diabetes later face heart disease, with the goal of guiding prevention.
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Better Blood Sugar Goals for Pregnant Women with Gestational Diabetes Who Are Overweight or Obese
This project looks at whether stricter blood sugar goals can help pregnant women who have gestational diabetes and are also overweight or obese have healthier pregnancies and babies.
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Understanding how gestational diabetes develops during pregnancy
This study is looking at how the body's insulin-producing cells change in pregnant women to better understand gestational diabetes and help improve diabetes care for moms both during and after pregnancy.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.