Improving gestational diabetes diagnosis using blood tests.

Glycemic Observation Using A1C for Gestational Diabetes Diagnosis

NIH-funded research Massachusetts General Hospital · NIH-11093431

This study is looking to make it easier and more accurate to diagnose gestational diabetes in pregnant women by improving how we use blood tests, so expectant moms can have a better experience and get the right care.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionMassachusetts General Hospital NIH-funded
Lab location1 site (Boston, United States)
Project IDNIH-11093431 on NIH RePORTER

What this research studies

This research focuses on enhancing the diagnosis of gestational diabetes mellitus (GDM) in pregnant women by optimizing the use of hemoglobin A1c (A1C) tests. Currently, pregnant women are screened using oral glucose tolerance tests, which can be cumbersome and inconsistent. The study aims to adjust A1C readings to account for changes in red blood cell behavior during pregnancy, thereby improving the accuracy of GDM detection. By leveraging advanced modeling techniques, the research seeks to provide a more reliable method for identifying hyperglycemia in expectant mothers.

Who could benefit from this research

Good fit: Ideal candidates for this research are pregnant women who are at risk for gestational diabetes, particularly those screened between 24-28 weeks of gestation.

Not a fit: Patients who are not pregnant or those who do not fall within the at-risk category for gestational diabetes may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to a simpler and more accurate method for diagnosing gestational diabetes, improving outcomes for mothers and their babies.

How similar studies have performed: Previous research has shown promise in using adjusted A1C measurements for diabetes diagnosis outside of pregnancy, indicating potential for success in this novel application.

Where this research is happening

Boston, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.