Peking University Weifang Birth Cohort
Peking University Birth Cohort in Weifang
This project will follow pregnant women in Weifang and their children to see if pre-pregnancy and prenatal exposures affect maternal and child health up to age 18.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 2800 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Peking University Academic / other |
| Locations | 1 site (Beijing, Beijing Municipality) |
| Trial ID | NCT06234332 on ClinicalTrials.gov |
What this trial studies
This is a prospective birth cohort enrolling pregnant women early in pregnancy in Weifang, China, with follow-up of mothers, fathers, and children from birth through childhood. Investigators collect detailed information on environmental, nutritional, and lifestyle exposures and record short- and long-term health outcomes. Multiple biological samples (blood, urine, placenta, cord blood, umbilical cord, and feces) are banked for future biomarker and mechanistic studies. Data linkage and repeated follow-up visits will allow study of how exposures before and during pregnancy relate to outcomes such as gestational diabetes, hypertension, and preterm birth and later child health.
Who should consider this trial
Good fit: Pregnant women at about 6–13+6 weeks who have lived in Weifang for at least six months, plan antenatal care and delivery at Weifang Maternal & Child Hospital, and their willing husbands and future children are ideal candidates.
Not a fit: People who live outside Weifang, plan to move away, cannot communicate normally, or expect immediate treatment changes from participation are unlikely to receive direct clinical benefit.
Why it matters
Potential benefit: If successful, the findings could help clinicians and public health programs prevent or reduce pregnancy complications and long-term health problems in mothers and children.
How similar studies have performed: Other large birth cohorts have successfully linked prenatal exposures to childhood and adult health outcomes, so this cohort follows an established, productive approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Pregnant woman 1. Pregnant women, 6-13\^+6 gestational weeks 2. Resided in Weifang in the past half years and have no plan to move out after delivery 3. Pregnant women who plan to have antenatal care and delivery in Weifang maternal\&Child Hospital. 4. Pregnant women who is willing to participate in this study with informed consent * Pregnant woman's husband 1. His wife was eligible for enrollment 2. He is the biological father of the child (his wife's current pregnancy) 3. Pregnant women's husband who is willing to participate in this study with informed consent * Offspring 4. Children born to pregnant women who met the inclusion criteria after enrolling in this study. 5\. Before the age of 8 years, his/her mother provided written informed consent. 6. After 8 years old, he/she agreed to continue this study and signed the informed consent. Exclusion Criteria: * Participants who cannot communicate normally.
Where this trial is running
Beijing, Beijing Municipality
- Peking University — Beijing, Beijing Municipality, China (Recruiting)
Study contacts
- Principal investigator: Haijun Wang, Ph.D — Peking University
- Study coordinator: Haijun Wang, Ph.D
- Email: whjun1@bjmu.edu.cn
- Phone: 86-010-82805583
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.