Comparing strict and permissive thresholds for treating gestational diabetes

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to evaluate the effects of different thresholds for initiating pharmacotherapy in patients with gestational diabetes (GDM). It compares a strict threshold, requiring two abnormal glucose values over a week, to a permissive threshold, where treatment is initiated if 50% of values are elevated. The study will assess maternal and neonatal outcomes to determine the most effective approach for managing GDM. By addressing the lack of consensus on treatment initiation criteria, this research seeks to standardize care for pregnant patients with GDM.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Live, non-anomalous fetus
* Literacy in English, Spanish, Mandarin, or Arabic
* Patients are also required to provide consent, demonstrate an understanding of the purpose of the study, and agree to the study protocol.

Exclusion Criteria:

* \<18 years at EDD
* pre-existing diabetes or diagnosis of GDM before 24 weeks
* multi-fetal gestation
* known major fetal anomaly
* known allergy to insulin
* chronic maternal corticosteroid use
* diagnosis of GDM based on finger sticks alone
* patients who have contraindication to oral glucose tolerance test
* a primary language other than English, Spanish, Mandarin, or Arabic

Where it's running

• Thomas Jefferson University
  Philadelphia, Pennsylvania, United States Recruiting
• University of Rochester Medical Center
  Rochester, New York, United States Not yet recruiting

Study contacts

• Study coordinator: Kavisha Khanuja, MD
• Email: kxk334@jefferson.edu
• Phone: 215-955-5000

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Understanding Gestational Diabetes in Asian Pregnant Women

  This study is trying to learn more about gestational diabetes in Asian pregnant women to see how different types of the condition affect their health and treatment options.

  Recruiting National University Health System, Singapore · Singapore · NCT06542718

• Comparing strict and permissive thresholds for treating gestational diabetes

  This study is testing whether treating gestational diabetes with stricter or more relaxed blood sugar targets leads to better health outcomes for mothers and their babies.

  Recruiting Thomas Jefferson University · Rochester, New York and 1 other locations · NCT06419803

• Early Glucose Patterns in Pregnant Women at Risk for GDM

  This study tests whether continuous glucose monitoring in early pregnancy can detect dysglycemia before GDM is diagnosed, in women with and without known risk factors.

  Recruiting DCB Research AG · Bern, Canton of Bern · NCT07783178

• Prenatal education to reduce environmental exposures during pregnancy

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  Recruiting at 2 sites The University of Texas Medical Branch, Galveston · Galveston, Texas and 1 other locations · NCT07758114

• Interprofessional Training to Improve Care for Peri-Delivery Patients with Substance Use Disorder

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  Recruiting University of Utah · Salt Lake City, Utah · NCT07707115

• Lower-extremity blood pressure monitoring during cesarean under spinal anesthesia

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  Recruiting Ohio State University · Columbus, Ohio · NCT07685730

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.