Investigating the effects of iron supplementation on glucose metabolism during pregnancy

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial examines the relationship between iron supplementation and glucose metabolism in pregnant women, specifically focusing on those with gestational diabetes and iron deficiency anemia. Participants will either refrain from taking iron supplements for 14 days or take a multivitamin containing iron while being monitored for changes in hepcidin levels and insulin sensitivity. The study aims to determine if high doses of oral iron can influence glucose metabolism and potentially impact pregnancy outcomes. The research is conducted at the Human Nutrition Laboratory ETH Zurich in collaboration with the University Hospital, Zürich.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* week of pregnancy 24-28
* pre-pregnancy BMI \<27.5kg/m2
* singleton pregnancy
* Hb \> 8.0 g/dl

Willing to either:

* not take any iron supplements for 14 days (however, participants will receive a similar amount of total iron during the 4 study days that they would normally receive over 14 days) OR
* to take the multivitamin "Burgerstein Schwangerschaft and Stillzeit" supplements over the 14 days (contains 30 mg iron)

Exclusion Criteria:

* iron infusion within the past 6 months
* severely anemic Hb\<8.0g/dl
* acute or chronic disease
* long-term medication
* medical problems known to affect iron homeostasis
* smoking

Where it's running

• Human Nutrition Laboratory ETH Zurich
  Zurich, Switzerland Recruiting

Study contacts

• Study coordinator: Nicole U Stoffel, PhD
• Email: nicole.stoffel@hest.ethz.ch
• Phone: +41 44 632 83 93

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.