Understanding how gestational diabetes develops during pregnancy
Elucidating the Pathophysiology of Gestational Diabetes Mellitus
This study is looking at how the body's insulin-producing cells change in pregnant women to better understand gestational diabetes and help improve diabetes care for moms both during and after pregnancy.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Mayo Clinic Rochester NIH-funded |
| Lab location | 1 site (Rochester, United States) |
| Project ID | NIH-11099798 on NIH RePORTER |
What this research studies
This research investigates the underlying mechanisms of gestational diabetes mellitus (GDM) by examining how maternal beta-cell function changes during early pregnancy and its implications for later development of diabetes. The project involves in vivo studies with pregnant women to analyze physiological data and identify risk factors for GDM. Dr. Egan, a trained endocrinologist, will work under the guidance of experienced researchers at Mayo Clinic to fill knowledge gaps and develop new insights into diabetes management during and after pregnancy.
Who could benefit from this research
Good fit: Ideal candidates for this research are pregnant women, particularly those at risk for developing gestational diabetes.
Not a fit: Patients who are not pregnant or those who have already been diagnosed with gestational diabetes may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for predicting and managing gestational diabetes, ultimately enhancing maternal and fetal health outcomes.
How similar studies have performed: Previous research has shown promising results in understanding diabetes mechanisms, but this specific focus on early pregnancy and beta-cell function is relatively novel.
Where this research is happening
Rochester, United States
- Mayo Clinic Rochester — Rochester, United States (Active)
Researchers
- Principal investigator: Egan, Aoife Maria — Mayo Clinic Rochester
- Study coordinator: Egan, Aoife Maria
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.