NIH-funded research R01 grant

HIV, gestational diabetes, and TB in pregnancy

Official title: HIV, gestational diabetes and TB in pregnancy

Funded at Weill Medical Coll of Cornell Univ · NIH-11398906 · Data updated 2026-11-12

This project looks at how HIV, gestational diabetes, and tuberculosis risk intersect during pregnancy to understand how to protect mothers and babies.

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Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionWeill Medical Coll of Cornell Univ
NIH-funded
Lab location1 site (New York, United States)
Project startJuly 15, 2022
Project endJune 30, 2027
Funding year2026
Award (this year)$690,173
NIH project number5R01AI162235-05
Project IDNIH-11398906 on NIH RePORTER

Who could benefit from this research

Could help

Pregnant women in high-prevalence areas for GDM and TB, especially those living with HIV and in their 2nd or 3rd trimester.

Less likely to help

Pregnant women without HIV or those not at risk for GDM/TB in the study region may not benefit from these findings.

What this research studies

The research follows pregnant women in a high-risk area to see how HIV and gestational diabetes affect the body's ability to fight TB during pregnancy and after delivery. Researchers will monitor participants through the 2nd and 3rd trimesters, at delivery, and up to 12 months postpartum, with glucose testing and immune assessments. The study uses blood tests and clinical data to describe how HIV and GDM influence TB risk and immune responses to M. tuberculosis over time. Findings could point to interventions to reduce TB risk in HIV-positive pregnant women and improve maternal and infant health.

Why it matters

Potential benefit: If successful, the work could lead to better screening and interventions to lower TB risk for HIV-positive pregnant women and improve pregnancy outcomes.

How similar studies have gone: Prior data suggest links among HIV, diabetes, and TB; this study aims to describe these relationships specifically in pregnancy.

Where this research is happening

  • Weill Medical Coll of Cornell Univ
    New York, United States
    Active

Researchers

  • Principal investigator: Mathad, Jyoti S — Weill Medical Coll of Cornell Univ
  • Study coordinator: Mathad, Jyoti S

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.