Condition

Pregnancy, High Risk clinical trials and research

• 16Clinical trials
• 7Countries

Newest Pregnancy, High Risk clinical trials

All recruiting trials (16)

• NOURISH: a community partnership to improve nutrition and glycemic control in pregnant women with pregestational diabetes

  Aiming to test a healthcare-community program that delivers healthy food weekly and provides nutrition education to pregnant women with type 1 or type 2 diabetes who have food insecurity, to improve blood sugar and pregnancy outcomes.

  Recruiting Ohio State University · Columbus, Ohio · NCT07560813

• MOCHA: Inpatient Mental Health Care for High-Risk Pregnancy

  This study tests a collaborative mental health program for pregnant or recently postpartum patients hospitalized for medical problems to see if it can be delivered feasibly and acceptably.

  Recruiting Indiana University · Indianapolis, Indiana · NCT07540585

• Permissive versus strict blood sugar control during labor for pregnant people with type 1 diabetes

  This trial will test whether allowing slightly higher blood sugars (70–140 mg/dL) during labor is as safe for newborns as keeping tighter control (70–110 mg/dL) for pregnant people with type 1 diabetes using hybrid closed‑loop insulin systems.

  Recruiting Phase 4 Ohio State University · Columbus, Ohio · NCT07293715

• Impact of Automated Insulin Delivery on Pregnancy Outcomes

  This study looks at how using automated insulin delivery systems during pregnancy affects the health of both mothers with type 1 diabetes and their babies.

  Recruiting University of California, San Francisco · San Francisco, California · NCT06654713

• Comparing Metformin and Insulin for Gestational Diabetes Treatment

  This study is testing whether metformin is as effective as insulin for treating gestational diabetes in pregnant people and looks at how safe both treatments are for mothers and their babies.

  Recruiting at 22 sites Phase 4 Ohio State University · Tuscaloosa, Alabama and 25 other locations · NCT06445946

• Improving management of preterm premature rupture of membranes with antibiotics

  This study is testing if a new combination of antibiotics can help pregnant people with preterm premature rupture of membranes stay pregnant longer and have healthier babies compared to the usual treatment.

  Recruiting at 2 sites Phase 4 Ohio State University · Columbus, Ohio and 1 other locations · NCT06396078

• Randomized comparison of immediate in-hospital 2-hour OGTT versus standard 4–12 week postpartum 2-hour OGTT for people with gestational diabetes

  This will test whether doing a 2-hour OGTT before hospital discharge gets more people who had gestational diabetes screened for diabetes than the usual 4–12 week outpatient test.

  Recruiting Ohio State University · Columbus, Ohio · NCT05909046

• Improving maternal and newborn health care access

  This study is trying to find ways to improve access to quality care for pregnant women and their newborns in low-resource areas to help them have healthier pregnancies and births.

  Recruiting at 2 sites George Washington University · Kintampo and 4 other locations · NCT05904145

• Evaluating Fertility Treatments in Women with Rheumatic Diseases

  This study is trying to see how well fertility treatments work for women with rheumatic diseases and if these treatments affect their health conditions.

  Recruiting IRCCS San Raffaele · Milan · NCT05807256

• Evaluating placental markers in pregnant women with and without antiphospholipid syndrome

  This study is trying to see if certain markers in the blood can help predict the risk of preeclampsia in pregnant women with antiphospholipid syndrome compared to those without it.

  Recruiting IRCCS San Raffaele · Milan · NCT05786235

• Observational study on the safety of relugolix therapy in pregnant women

  This study is trying to see if relugolix therapy is safe for pregnant women and their babies by looking at health outcomes during and after pregnancy.

  Recruiting Sumitomo Pharma Switzerland GmbH · Wilmington, North Carolina · NCT05739123

• Improving blood sugar control during pregnancy for women with type 2 diabetes using technology and coaching

  This study is testing whether using a mobile app and coaching can help pregnant women with type 2 diabetes better control their blood sugar compared to regular prenatal care.

  Recruiting Ohio State University · Columbus, Ohio · NCT05662462

• Early screening to find gestational diabetes in pregnancy

  This project tries a first-trimester blood screening to see if it finds gestational diabetes earlier in pregnant people at high risk.

  Recruiting University of Massachusetts, Worcester · Worcester, Massachusetts · NCT05388643

• Using continuous glucose monitors during pregnancy for women with type 2 diabetes

  This study is testing if using continuous glucose monitors during pregnancy can help women with type 2 diabetes manage their blood sugar better and have healthier babies compared to the usual fingerstick method.

  Recruiting University of Massachusetts, Worcester · Worcester, Massachusetts · NCT05317585

• Comparing glycemic targets in overweight and obese women with gestational diabetes

  This study tests whether setting stricter blood sugar goals during pregnancy helps overweight and obese women with gestational diabetes have better outcomes for themselves and their babies.

  Recruiting at 5 sites Indiana University · Birmingham, Alabama and 4 other locations · NCT05124808

• Examining anticoagulation in pregnant women using Lovenox three times a day

  This study tests if giving pregnant women Lovenox three times a day helps keep their blood thinner and safer from clots compared to the usual twice-daily dose.

  Recruiting Phase 4 University of California, Irvine · Orange, California · NCT04861103

Related topics

Quick answers

How many Pregnancy, High Risk clinical trials are recruiting right now?

16, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 7 countries. The most sites are in United States (13 trials), Italy (2 trials), Ghana (1 trial), India (1 trial), Kenya (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 4: 4. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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