Early Glucose Patterns in Pregnant Women at Risk for GDM

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a decentralized observational pilot study in Switzerland enrolling 48 pregnant women around 12 weeks gestation. Participants wear a blinded CGM device for 12–16 weeks to record glucose levels throughout the day. The goal is to identify CGM-derived thresholds and patterns that differentiate those at higher risk for GDM from those at lower risk, prior to routine GDM screening. The study compares glucose dynamics between groups with and without established GDM risk factors to see if early dysglycemia can be detected before the standard OGTT window. No interventions are applied; data collection focuses on glucose monitoring and analyses of exposure duration and intensity.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Female sex
* Aged ≥18 years at inclusion
* Pregnant with singleton ≤12 GW
* Willingness to wear a CGM device for 12-16 weeks
* Signed informed consent

Exclusion Criteria:

* Pre-existing type 1 or type 2 diabetes mellitus or known prediabetes
* Diagnosis of GDM during current pregnancy
* Known allergy to adhesive materials or sensor components
* Inability to follow procedures or insufficient knowledge of project languages (German, French or English)
* Inability to give consent.

Where it's running

• DCB Research AG
  Bern, Canton of Bern, Switzerland Recruiting

Study contacts

• Study coordinator: Martina Rothenbühler, PhD
• Email: martina.rothenbuehler@dcberne.com
• Phone: +41792628989

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.