Randomized comparison of immediate in-hospital 2-hour OGTT versus standard 4–12 week postpartum 2-hour OGTT for people with gestational diabetes

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Adults with gestational diabetes delivering at The Ohio State University Wexner Medical Center are randomized during their delivery admission to an immediate inpatient 75-g, 2-hour OGTT before discharge or the usual outpatient 4–12 week 75-g, 2-hour OGTT in a pragmatic, non-blinded design. The primary goal is to increase the frequency of postpartum diabetes screening, with outcomes including OGTT completion rates and detection of impaired glucose tolerance or diabetes. A linked PP CARE component follows English-speaking DIP participants 12–24 months postpartum using surveys and qualitative interviews to identify barriers and facilitators to cardiovascular health counseling and risk-reduction, including social determinants of health and structural factors. The study uses patient-centered mixed methods to inform implementation of postpartum screening strategies at a single large academic medical center.

Why it matters

Who can join: the full rules

DIP - Inclusion Criteria:

* Immediately postpartum individuals during their delivery hospital admission
* ≥ 18 years old with the ability to give informed consent.
* Diagnosed with GDM during pregnancy by:

  * Elevated one-hour 50-gram glucose challenge test any time during pregnancy AND provider documentation of gestational diabetes (NOT pregestational diabetes) diagnosis OR
  * Two elevated values on a 3-hour 100-gram glucose tolerance test any time in pregnancy AND provider documentation of gestational diabetes (NOT pregestational diabetes) diagnosis
* English or Spanish speaking
* Receiving prenatal and postpartum care at OSU

DIP- Exclusion Criteria:

* Individuals who cannot tolerate a 2-hour oral glucose tolerance test (OGTT) (i.e. history of gastric bypass)
* Not English or Spanish speaking

PP CARE Inclusion criteria: Enrolled DIP participants who are English speaking will be eligible for PP CARE follow up if they are between 12 and 24 months postpartum.

PP CARE Exclusion criteria: Spanish speaking DIP participants will be excluded because the study team does not include anyone who is Spanish speaking.

Where it's running

• The Ohio State University Wexner Medical Center OB/GYN Maternal and Fetal Medicine
  Columbus, Ohio, United States Recruiting

Study contacts

• Principal investigator: Christine Field, MD, MPH — Ohio State University
• Study coordinator: Kartik Venkatesh, MD, PhD
• Email: kartik.venkatesh@osumc.edu
• Phone: 614-293-2222

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.